All the pharmaceutical products formulated for systemic delivery via the oral route of administration, irrespective of the mode of delivery (immediate, sustained or controlled release) and the design of dosage form (solid dispersion or liquid), must be developed within the intrinsic characteristics of GI physiology. The recent scientific and patented literature concluded that an increased inter...

A study of dosage requirements undertaken among chronic OPD patients found on unnecessarily high drug dosage regimes. Basing on OPD experiences authors discuss long term treatment strategies and strongly advocate low dose intermittent oral therapy.

The objective of a medicinal formulation development project is to deliver drug to the patient in the required amount, at the required rate, consistently within a batch, from batch to batch, and over the product’s shelf life. To produce a drug substance in a final dosage form requires pharmaceutical ingredients. In selecting excipients for pharmaceutical; dosage forms and drug products the deve...

Novel drug delivery systems for controlled-release of opioid agonists as a long time painkillers or opioid antagonists for opium, heroin, and alcohol addiction are under development or in clinical use today. In this article, the field of “new drug delivery systems” is momentarily reviewed from the viewpoint of the marketed opioid agonists/antagonists dosage forms today.