Tuberculosis is treated with a group of drugs that need to be used over a long period of time and isoniazid is the major drug in this group. Antituberculosis drug-induced hepatitis is the most serious problem in tuberculosis treatment. The enzyme N-acetyltransferase-2 (NAT-2) metabolizes isoniazid in the liver so it is considered to cause hepatotoxicity. The association of polymorphic NAT acety...

Viral hepatitis is a common disease caused by various hepatotropic viruses. An awareness of the characteristics and transmission patterns of these viruses will help nurses to understand the diverse clinical outcomes of infection and develop effective patient education and infection prevention and control strategies.

conclusions the obtained results showed that hcv infection was an alarming problem among opiate users in the eastern part of turkey. it is suggested to rapidly diagnose the infected persons; thus preventive measures and appropriate control may limit further transmission of these infections. background hepatitis b, hepatitis c and hiv infections constitute serious healthcare problems worldwide. ...

Hepatitis B is a serious public health problem. The state of Santa Catarina presents areas of high endemicity. The aim of this study was to describe temporal trends in detection rates of hepatitis B in the period from 2002 to 2009 in Santa Catarina and in its regions. A time series study was carried out. Crude rates were calculated and standardized by age using the direct method. Annual variati...

The elimination viral hepatitis requires increased awareness of the viruses that cause it by the general population. To this end, the Iran Hepatitis Network held the First Drawing and Illustration Contest with the theme of eliminating hepatitis. We suggest that artwork provided by the general public could have a role in campaigns promoting hepatitis elimination.

introduction and objectives: tuberculosis (tb) still remains a major health concern both in developing and developed countries. the rate of the liver injury due to anti-tb drugs in developed countries has been reported up to 4%. the goal of this study is to assess the rate and risk factors for anti-tuberculosis drug-induced liver injury (dili). also, a model has been designed to predict dili in...

A hepatitis A outbreak has occurred in Chile since November 2016. Men are predominantly affected, with a large proportion of men who have sex with men (MSM). We describe 12 consecutive unrelated confirmed cases who presented at our healthcare institution in Santiago Metropolitan Area. Nine were men, all reporting having had sex with men. Ten viral sequences, genotyped as IA, clustered with the ...