Artemisinin is used to treat multi-drug resistant strains of malaria and also in the early stages development as an anti-cancer drug.

The worldwide dissemination of multi drug resistant Acinetobacter baumannii strains has caused serious concern and high rate of mortality in recent decades that originate from limited effective antibiotics in the treatment of A. baumannii infections. Myxobacteria are Gram-negative bacteria that are important for their complex lifestyle and production of novel structurally secondary metabolites ...

Background: Drug-Resistant Tuberculosis (DR-TB) is one of the major public health issues globally. Zambia highly burdened by TB and multi-drug resistant TB. In this study, sputum samples obtained from new previously treated cases were examined for drug-resistant Mycobacterium tuberculosis (MTB). Methods: Sputum specimens processed using N-acetyl-L-cysteine-sodium hydroxide method, stained fluor...

CLINICAL QUESTION What is the best approach to the treatment of drug-resistant tuberculosis (TB)? RESULTS Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively drug-resistant T...

Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any fluoroquinolone, and at least one of three injectable second-line drugs (amikacin, capreomycin, or kanamycin). The definition has applicable clinical value and has allowed for more uniform surveillance in varied international settings...

Drug resistant tuberculosis (DRTB) has hit the tuberculosis control programs like a thunderbolt. It has challenged all the aspects of tuberculosis management, from diagnosis till prognosis. India has had a major contribution in DR TB worldwide, with Mumbai city being the niche for DRTB strains. DRTB has emerged distinctly as a “Creation of mankind” than solely as a “Weapon of God” to curtail th...

Despite the prevalence of different kinds of wounds among people around the world, challenges ahead for managing wound healing continues. One of the most important issues for wound healing is infection that can delay healing process. Also, drug-resistant infections are growing as a worrying challenge in medicine. A lot of studies done over different methods to improve wound healing process, whi...

Streptococcus pneumoniae remains a major cause of infection in both children and adults, annually resulting in significant morbidity and mortality. The past two decades have seen an alarming worldwide increase in the incidence of drug-resistant S. pneumoniae (DRSP). DRSP is now common throughout the United States, and physicians are questioning how best to approach this epidemic. With the intro...