the present study has been directed to investigate ursodeoxycholic acid (udca) effect in children, to reduce the high liver transaminases induced by anticonvulsant drugs (drug induced hepatitis). this idea has been driven from cytoprotective and antioxidant properties of udca to be used in drug induced inflammation in liver. twenty two epileptic patients aged between 4 mo - 3 yr whom were under...

background: besides the well-known adverse effects of valproate (vpa), disorders related to male reproductive functions have been reported. furthermore, only a limited number of previous studies have reported the relationship between vpa dose and impairment of the hormonal axis and semen quality. a patient with reversible changes that occurred in the sperm parameters after a dose increment of v...

objectives: the aim of this randomized clinical trial was to assess the efficacy of stimdate compared to ritalin in the treatment of children with attention deficit hyperactivity disorder (adhd). method: sixty four subjects (45 boys and 15 girls) aged 5-13 who were diagnosed with adhd based on (dsm-iv-tr) criteria were selected for this study. the subjects were randomly assigned to two groups: ...

background : drug abuse is one of the important challenges in the field of mental health and adolescence health promotion. because of the social and medical cost of drug abuse and its consequences among youth people, it is necessary to intervene effectively. this theoretical based study explained predictability of the theory of planned behaviour (tpb) on drug abuse related behaviours. methods :...

objectives: anticonvulsant drugs can cause various forms of skin drug reactions, ranging from exanthema to severe blistering reactions. some studies have reported an association between hla-b*1502 allele and severe skin reactions. materials and methods: fifteen patients with severe skin reactions following treatment with anticonvulsant drugs (carbamazepine, lamotrigine, phenobarbital, primidone...

OBJECTIVES To describe the various factors that come into play when a breast-feeding mother is taking medications, including use of prescription drugs, over-the-counter medications, recreational drugs, galactogogues, and herbal remedies and to provide a framework used for counseling breast-feeding women. SETTING Community and hospital pharmacy and health care settings. PRACTICE DESCRIPTION ...