Recently, differential scanning calorimetry (DSC) has been acknowledged as a novel tool for diagnosing and monitoring several diseases. This highly sensitive technique has been traditionally used to study thermally induced protein folding/unfolding transitions. In previous research papers, DSC profiles from blood samples of patients were analyzed and they exhibited marked differences in the the...

RATIONALE AND OBJECTIVES To assess if preradiation and early follow-up measurements of relative regional cerebral blood flow (rrCBF) can predict treatment outcome in patients with cerebral metastases and to evaluate rrCBF changes in tumor and normal tissue after stereotactic radiosurgery using arterial spin-labeling (ASL) and first-pass dynamic susceptibility-weighted contrast-enhanced (DSC) pe...

This paper describes the integration of interactive statistical graphics within R using state-of-the art R-connectivity. The iPlots project uses SJava to deliver interactive plots for R and an associated framework for their customization. The graphical part of iPlots is implemented in Java. The design is discussed and some practical examples of iPlots are illustrated.

Kriging is one of the most often used prediction methods in spatial data analysis. This paper examines which steps of the underlying algorithms can be performed in parallel on a PVM cluster. It will be shown, that some properties of the so called kriging equations can be used to improve the parallelized version of the algorithm. The implementation is based on R and PVM. An example will show the...

BACKGROUND The Food and Drug Administration (FDA) issues drug safety communications (DSCs) to health care professionals, patients, and the public when safety issues emerge related to FDA-approved drug products. These safety messages are disseminated through social media to ensure broad uptake. OBJECTIVE The objective of this study was to assess the social media dissemination of 2 DSCs release...

BACKGROUND AND PURPOSE To compare the diagnostic performance of arterial spin-labeling (ASL) and dynamic susceptibility contrast (DSC) perfusion in detecting cerebral blood flow (CBF) changes before and after endovascular recanalization in acute ischemic syndrome. METHODS The inclusion criteria for this retrospective study were patients with acute ischemic syndrome who underwent endovascular ...

STUDY QUESTION Is there a relationship between decidualization and apoptosis of decidual stromal cells (DSC)? SUMMARY ANSWER Decidualization triggers the secretion of soluble factors that induce apoptosis in DSC. WHAT IS KNOWN ALREADY The differentiation and apoptosis of DSC during decidualization of the receptive decidua are crucial processes for the controlled invasion of trophoblasts in ...

PURPOSE We evaluated the diagnostic performance of histogram analysis of data from a combination of dynamic susceptibility contrast (DSC)-MRI and dynamic contrast-enhanced (DCE)-MRI for quantitative differentiation between central nervous system lymphoma (CNSL) and high-grade glioma (HGG), with the aim of identifying useful perfusion parameters as objective radiological markers for differentiat...