نتایج جستجو برای: duration of action

تعداد نتایج: 21194574  

Journal: :British journal of anaesthesia 1988
J E Caldwell K P Castagnoli P C Canfell M R Fahey D P Lynam D M Fisher R D Miller

The pharmacokinetics of pipecuronium 0.07 mg kg-1 and pancuronium 0.1 mg kg-1 were compared in 39 ASA class I or II patients. Plasma concentrations of these agents were measured for 6 h following administration, using a sensitive and specific capillary gas chromatographic assay. Concentration v. time data were analysed by non-linear regression and fitted to a two- or three-compartment model as ...

Journal: :physiology and pharmacology 0
parvin zareian neuroscience research center, shaheed beheshti univ.med sci., tehran, iran mahyar janahmadi seyed mohamamd firoozabadi fereshteh motamedi

ion channels are responsible for control of cell function in excitable tissues such as heart and brain and also in organs and tissues traditionally thought to be non- excitable including liver and epithelium. in the present research, the effect of lead (pb2+) on ca2+ -dependent action potential and currents was studied in f77 neuronal soma membrane of helix aspersa. for this purpose, action pot...

Journal: :American journal of critical care : an official publication, American Association of Critical-Care Nurses 2009
Philipp Fassbender Götz Geldner Manfred Blobner Rainer Hofmockel Christopher Rex Shiva Gautam Atul Malhotra Matthias Eikermann

BACKGROUND The duration of action of neuromuscular blocking drugs (NBDs) varies between individuals and even within individuals in different settings. OBJECTIVES To define predictors of variance in duration of action of rocuronium and cisatracurium administered long-term. METHODS A prospective, double-blind, multicenter trial that included 113 patients scheduled for major abdominal surgery ...

Journal: :research in molecular medicine 0
reza valadan molecular and cell biology research center, faculty of medicine, mazandaran university of medical sciences, sari, iran alireza rafiei molecular and cell biology research center, faculty of medicine, mazandaran university of medical sciences, sari, iran mohsen tehrani molecular and cell biology research center, faculty of medicine, mazandaran university of medical sciences, sari, iran forough nejatollahi recombinant antibody laboratory, department of immunology, faculty of medicine, shiraz university of medical sciences, shiraz, iran

production and approval of trastuzumab (herceptin®) for the treatment of metastatic breast cancer (mbc) was a millstone in antibody-based targeted therapy in the cancer treatment. however, despite the early success in the clinical trials, trastuzumab failed to appreciate the initial attraction due to development of resistance to the drug. the majority of patients who benefit from the drug acqui...

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