In recent decades, three generations of thiomers have been developed with the main purpose obtaining enhanced interactions mucosal tissues. Therefore, many different types thiolated ligands generated and attached to polymeric backbones. The aim this study was synthesize all directly compare their properties regarding mucus penetration mucoadhesion. Starting from pectin, unprotected thiomer pect...

background: in this experimental study, the radiographic and biomechanical characteristics of osteoperforated rabbit tibia during bone repair period were investigated. materials and methods: using dental drills, 2 mm holes were drilled at the mid-shaft of right tibia in 12 new zealand white rabbits. the left tibia was intact and selected as the control. x-rays of the left and right tibias were ...

DYOPTYKA’s innovative solution for the reduction of speckle noise in projection displays, using a phase randomizing deformable mirror, is shown to achieve good performance both within a single 1 μs pulse duration and through sequences of such pulses.

Aim: Mucoadhesive buccal films provide drug delivery for both local and systemic circulation with increased patient compliance. The objective of this study was to develop a film containing benzydamine hydrochloride (BNZ) by using hyaluronic acid (HA) as film-forming agent glycerin (Gly) plasticizer the anti-inflammatory effect on mucosal ulcer. Material Methods: effects different concentrations...

Background/Aim. Vinegar is one of the main international traditional nutraceuticals, and it has been used as a vaginal health protectant due to vagina pH balance maintenance antimicrobial properties. Since form vinegar liquid, difficult apply vaginally its short retention. The aim this study was design mucoadhesive gel made vinegar. Methods. Xanthan gum tragacanth were utilized natural gel-form...

Studies using infrared, (1)H and (13)C nuclear magnetic resonance, and X-ray photoelectron spectroscopies and differential scanning calorimetry support the hypothesis that hydrogen bonds, formed between the carboxylic acid functionality of the mucoadhesive material poly(acrylic acid) and the glycoprotein component of mucus, play a significant role in the process of mucoadhesion. There are fewer...

Multilamellar liposomes consisting of dipalmitoyl phosphatidylcholine (DPPC) and dicetyl phosphate (DCP) in a molar ratio of 8:2 (DPPC:DCP = 8:2) were coated with three different types of polymers: chitosan, polyvinyl alcohol having a long alkyl chain, and poly(acrylic acid) bearing cholesterols. The existence of polymer layers on the liposome surface was confirmed by measuring the zeta potenti...

the purpose of this research was to formulate and systemically evaluate in-vitro and in-vivo performances of mucoadhesive propranolol hydrochloride microspheres for its potential use in the treatment of hypertension, myocardial infraction and cardiac arrhythmias. propranolol hydrochloride mucoadhesive microspheres, containing carbopol-934p as mucoadhesive polymer and ethyl cellulose as carrier ...