We report the nanomechanical microcantilevers operated in vibration modes (oscillation) with use of RNA aptamers as receptor molecules for label-free detection of hepatitis C virus (HCV) helicase. The nanomechanical detection principle is that the ligand-receptor binding on the microcantilever surface induces the dynamic response change of microcantilevers. We implemented the label-free detecti...

We demonstrate a rupture front focusing phenomenon at the initial stage of earthquake, which causes high slip rate pulses and therefore generates high frequency seismic waves. In this computation, we assume a pre-slip region, where stress has already lowered quasi-statically to the dynamic friction level. And due to the pre-slip, we suppose a stress concentration at the edge of pre-slip area. T...

The article demonstrates that computational modeling has the capacity to convert metabolic snapshots, taken sequentially over time, into a description of cellular, dynamic strategies. The specific application is a detailed analysis of a set of actions with which Saccharomyces cerevisiae responds to heat stress. Using time dependent metabolic concentration data, we use a combination of mathemati...

Pre-stress techniques tend to increase cross-sectional capacity and optimize design. Such features have made these techniques rather popular. Over time, these structures tend to fail, and the reduction of pre-stress force over the lifetime of the structure is said to be one of the most significant destructive factors in these structures. This decrease in force occurs due to various reasons. In ...

(DO) is considered the most important water quality variable in fish culture. In the broadest sense, however, dissolved oxygen concentration is no more important than other environmental variables because any factor that is outside the range tolerated by fish can cause stress or death. What makes dissolved oxygen concentration so important in intensive fish culture is the speed with which it ca...

3D numerical method is presented for simulation of foam formation and dynamics in viscous flows in the presence of insoluble surfactant and under the influence of van der Waals forces. The mathematical model is based on the Stokes equations in the fluid phases, coupled with velocity and stress boundary conditions at the interfaces. A nonuniform surfactant concentration on the interfaces, govern...

OBJECTIVE The aim of the present study was to investigate influence of oxidative stress on newborn organism, in terms of the dynamics of malondialdehyde (MDA) concentration changes and of the activities of selected antioxidants in asphyxial newborns on the 1st and 5th day of life. METHOD In the group of 62 preterm and term asphyxial newborns, characterized by the presence of asphyxial criteri...

Field-induced static and dynamic yield stresses are explored for magnetorheological (MR) suspensions in an aging, yield stress matrix fluid composed of an aqueous dispersion of Laponite clay. Using a custom-built magnetorheometry fixture, the MR response is studied for magnetic field strengths up to 1 T and magnetic particle concentrations up to 30 v%. The yield stress of the matrix fluid, whic...

BACKGROUND Plasma fibrinogen is considered as a positive mediator between mental stress and cardiovascular disease because it is an acute-phase protein released in response to mental stress and a coagulation factor. However those three factors have never been studied together within a single integrated framework, using cardiac troponin T as a marker of cardiovascular risk. METHODS 491 disease...