necroses. Microscopic examination disclosed 2 patterns, the one with diffuse arrangement of small cells with scanty cytoplasm and the other with follicles varying from small to large with eosinophilic fluid in the lumen. In the 2nd pattern, the tumor cells had abundant eosinophilic cytoplasm. Mitotic figures were numerous (> 30 mitoses/high power field (HPF)). Immunohistochemically, the tumor’s...

Patients with Turner syndrome (TS) require close medical follow-up and management for cardiac abnormalities, growth and reproductive issues. This review summarizes current controversies in this condition, including: 1) the optimal genetic testing for Turner syndrome patients, particularly with respect to identification of Y chromosome material that may increase the patient's risk of gonadoblast...

a seventeen-years old woman was presented with infertility and primary amenorrhea. she had normal stature, femate phenotype and normal development of breasts, external genitalia, vagina and cervix. pelvic examination showed a large lobulated mass. on sonography there was a mass with probable origin of ovary. paraclinic tests were carried out. gonadotropins were in postmeno pausal limits. alpha ...