Following a brief overview of the diagnostic criteria and epidemiology of major depressive disorder (MDD), we describe the current major empirically supported theories of depression and the therapies based on them. We begin the discussion of the assessment by describing diagnostic assessment tools. Next, we discuss using the general theories and therapies of depression described in the % rst pa...

INTRODUCTION L-Acetylcarnitine (LAC), the acetyl ester of carnitine naturally present in the central nervous system and involved in several neural pathways, has been demonstrated to be active in various animal experimental models resembling some features of human depression. The aim of the study is to verify whether LAC can have an antidepressant action in a population of elderly patients with ...

Suicidal ideation and attempts are a major public health problem. Research has identified many risk factors for suicidality; however, most fail to identify which suicide ideators are at greatest risk of progressing to a suicide attempt. Thus, the present study identified predictors of future suicide attempts in a sample of psychiatric patients reporting suicidal ideation. The sample comprised 4...

Dementia increases with age, with an overall prevalence in Canada of 8% in those 65 years and older, 2.4% in those aged 65 to 74 years, 11.1% in those aged 75 to 84 years, and 34.5% in those aged 85 years and older.1 Alzheimer’s disease (AD) is thought to be the most common type of dementia in all age groups. How ever, younger age groups are more likely than older age groups to be diagnosed wit...

BACKGROUND Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS). METHODS A case-control, retrospective analysis was performed. Differences in characteristics between the groups, RLS and those with no sleep disorder (NSD), were determined using χ2 tests. Cox proportional hazard re...

objectives: according to growing of aged population in iran and also high prevalence of psychiatric disorders in this group, assessment of demographical and epidemiological studies of psychiatric disorders in subjects 59 years or older in ekbatan district of tehran was the aim ofthis study. methods & materials: the subjects were chosen randomly from 1422 subjects 59 years or older, who were liv...

Currently it is estimated that 3-8% of women of reproductive age meet strict criteria for premenstrual dysphoric disorder (PMDD). Assessment of published reports demonstrate that the prevalence of clinically relevant dysphoric premenstrual disorder is probably higher. 13-18% of women of reproductive age may have premenstrual dysphoric symptoms severe enough to induce impairment and distress, th...

OBJECTIVES To examine the association of life events and social support in the broadly defined category of depression in late life. INTRODUCTION Negative life events and lack of social support are associated with depression in the elderly. Currently, there are limited studies examining the association between life events, social support and late-life depression in Brazil. METHODS We estimat...

BACKGROUND We aimed to examine the course of depression during 2-year follow-up in a group clinically depressed older persons. Subsequently, we studied which socio-demographic and clinical characteristics predict a depression diagnoses at 2-year follow-up. METHODS Data were used from the Netherlands Study of Depression in Older persons (NESDO; N = 510). Diagnoses of depression DSM-IV-TR crite...

Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute, Psykoterapienheten City, Karlavägen 53, 11449 Stockholm, Sweden 2 Transcultural Centre, Stockholm County Council, S:t Göran’s Hospital, Stockholm Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute, S:t Göran’s Hospital, Stockholm Department of Clinical Neuroscience, Psychiatry Section, Karo...