Apolipoprotein E (apo E) is a structural constituent of several serum lipoprotein classes. It plays an important role in lipid metabolism by acting as a ligand for low-density lipoprotein (LDL) and chylomicron remnant receptors. Three common alleles called e2, e3 and e4 have been described, which code for three protein isoforms (E2, E3 and E4). The polymorphism is clinically significant, and it...

apolipoprotein e (apo e) is a structural constituent of several serum lipoprotein classes. it plays an important role in lipid metabolism by acting as a ligand for low-density lipoprotein (ldl) and chylomicron remnant receptors. three common alleles called e2, e3 and e4 have been described, which code for three protein isoforms (e2, e3 and e4). the polymorphism is clinically significant, and it...

Early region 4 (E4) of bovine adenovirus type 3 (BAV-3) was analyzed by Northern blotting, RT-PCR analysis, cDNA sequencing, and S1 nuclease protection assays. The transcriptional map of the E4 region of BAV-3 has marked dissimilarities from those of mouse adenovirus-1, ovine adenovirus-287, and human adenovirus-2, for which the transcriptional maps have been constructed. The E4 region of BAV-3...

The presence of the e4 allele of the apolipoprotein E (APOE) gene is the best-known genetic risk factor for Alzheimer's disease. In this study, we investigated the link between functional and behavioural differences and regional brain volume and cortical thickness differences in those who carry the e4 allele (e4+) and those who only carry the e3 allele (e3/e3). We studied these genotype populat...

The presence of the e4 allele of apolipoprotein E (APOE) gene is the best known genetic risk factor for Alzheimer’s disease. In this study we investigated the link between functional and behavioural differences and regional brain volume and cortical thickness differences between those that carry the e4 allele (e4+) and those that only carry the e3 allele (e3/e3). We studied these genotype popul...

El mango cv. Tommy Atkins es cultivado en el departamento del Tolima, principalmente, lugar donde expresa su mejor comportamiento agronómico y calidad de la fruta. objetivo fue evaluar estado nutricional las plantas cuantificar extracción nutrientes por fruta función orden suelo se cultiva. Las concentraciones cada nutriente variaron entre fases muestreadas órgano (hojas, flor fruto) (Entisol e...

Background: The apolipoprotein E (apoE) e4 allele has been shown to be a risk factor for dementia, but it is not clear to what extent apoE affects overall cognitive function in non-demented elderly subjects, or how this risk may be modified by gene–environment interactions. Objective: To examine changes in cognitive function in elderly people as a function of the apoE e4 phenotype. Methods: A c...

PURPOSE Exendin-4 (E4), a long-acting agonist of the hormone glucagon-like peptide 1 receptor (GLP-1R), is administered to treat type II diabetes in the clinical setting and also shows a neuroprotective effect. Our previous studies demonstrated its protective effect in early experimental diabetic retinopathy (DR), but the molecular and cellular mechanisms are largely unknown. This study aimed t...

Soybean (Glycine max) cultivars adapted to high latitudes have a weakened or absent sensitivity to photoperiod. The purposes of this study were to determine the molecular basis for photoperiod insensitivity in various soybean accessions, focusing on the sequence diversity of the E4 (GmphyA2) gene, which encodes a phytochrome A (phyA) protein, and OPEN ACCESS Agronomy 2013, 3 118 its homoeolog (...

BACKGROUND No previous study examined a disease modifying effect of APOE E4 status on the association between the urinary albumin-to-creatinine ratio (UACR) and cognition. This study aimed to investigate whether APOE E4 modified the association in Korean adults. METHODS We performed a cross-sectional study in adults aged 45 to 74 who were living in Namwon City, Republic of Korea. Cognitive fu...