Using DNA subtractive hybridization, 49 unique gene segments were identified from a strain of Streptococcus mutans that was isolated from a patient with severe early childhood caries (S-ECC). Further hybridization with DNA from other S. mutans strains isolated from both caries-active and caries-free subjects yielded five unique sequences of DNA common to strains associated with S-ECC.

Early childhood caries (ECC) has been regarded as one of the most prevalent chronic diseases in early childhood. Many studies show ECC was often neglected and most of the decay was left untreated [1]. Early treatment of ECC is important because untreated caries can lead to pain, sepsis and spreading infection, malnutrition due to the inability to eat, and poor general health. Children with seve...

Hintergrund: Karies im Milchgebiss kommt bei mehr als 500 Mio. Kindern weltweit vor. Diese hohe Prävalenz macht die Erkrankung zu einem globalen Gesundheitsproblem. Der Zusammenhang zwischen und Stillen ist noch nicht vollständig geklärt wird in der Literatur zudem kontrovers diskutiert. Ziel Arbeit: Studie war Überprüfung des Zusammenhangs Stilldauer (ausschließliches dann sich anschließendes ...

BACKGROUND Dental caries is a major problem in preschool children. The contribution of saliva in providing defense during caries process is of primary importance. pH buffer capacity through bicarbonate, phosphate and protein buffer systems have universal acceptance as a caries defense mechanism. Antioxidant capacity of saliva can constitute a first line of defense against chronic degenerative d...

Severe early childhood caries remains the most common chronic disease affecting children. The multifactorial etiology of caries has established a controversy about which risk factors were more significant to its development. Therefore, our study aimed through meticulous statistical analysis to arrange the "well agreed upon" common risk factors in order of significance, to aid the clinician in t...