OBJECTIVE To determine whether the use of inhaled corticosteroids during pregnancy increases the risk of pregnancy induced hypertension and pre-eclampsia among asthmatic women. DESIGN Nested case-control study. SETTING Three administrative health databases from Quebec: RAMQ, MED-ECHO, and Fichier des evenements demographiques. PARTICIPANTS 3505 women with asthma, totalling 4593 pregnancie...

OBJECTIVE To examine the association between hypertensive diseases of pregnancy (gestational hypertension and pre-eclampsia) and the development of circulatory diseases in later life. DESIGN Cohort study of women who had pre-eclampsia during their first singleton pregnancy. Two comparison groups were matched for age and year of delivery, one with gestational hypertension and one with no histo...

Introduction: Pre-eclampsia is a multiorgan disorder unique to pregnancy typically characterized by blood pressure ≥140/90 mm Hg after 20 weeks gestation. Aim: To determine maternal and fetal outcomes in patients diagnosed with pre-eclampsia. Materials and Methods: This was a retrospective, observational study done by analysis of hospital records of patients admitted in Hospital with diagnosis ...

Objective To determine whether the use of inhaled corticosteroids during pregnancy increases the risk of pregnancy induced hypertension and pre-eclampsia among asthmatic women. Design Nested case-control study. Setting Three administrative health databases from Quebec: RAMQ, MED-ECHO, and Fichier des événements démographiques. Participants 3505 women with asthma, totalling 4593 pregnancies, bet...

The aims of Ballantyne's first book on promaternity (antenatal) care were: * The antenatal diagnosis of monsters * The treatment of monsters * The prevention of fits. The last concerns eclampsia, so care has been concerned with eclampsia from the earliest days. One of the original aims of promaternity care in 1901 was the prevention of fits and convulsions due to eclampsia, which was often asso...

Pre-eclampsia and eclampsia are hypertensive disorders of pregnancy that cause significant morbidity and mortality in the fetus and mother both in the developed and developing countries.[1] In Nigeria, they are listed as one of the top three causes of maternal mortality.[2-8] Ultimately, the only “cure” for pre-eclampsia and eclampsia is delivery of the baby. However, maternal and perinatal dea...

BACKGROUND Lead toxicity is a prevalent health problem in both developed and developing countries. One of the proposed mechanisms for lead-induced organ damage is oxidative stress. Oxidative stress is well-associated with the pregnancy disorder, pre-eclampsia. Exposure to lead may be one of the sources of the oxidative stress that leads to development of pre-eclampsia in pregnant women. OBJEC...

BACKGROUND Eclampsia remains one of the major causes of maternal morbidity and mortality especially in the developing countries. In Nigeria, it is the 3 rd commonest cause of maternal mortality. The high maternal morbidity and mortality due to eclampsia in the developing countries has been ascribed to late referral, delay in hospitalization, lack of transport, unbooked status of patients and mu...

AIM This study investigated whether post-partum insulin resistance existed in women with a history of severe pre-eclampsia. METHODS The euglycemic hyperinsulinemic clamp technique was used to assess insulin sensitivity at least 6 months after delivery in 13 women who had had severe pre-eclampsia and 26 age- and body mass index-matched controls who had had normal pregnancy. RESULTS The mean ...