Introduction Sleep deprivation and electroconvulsive therapy (ECT) effectively ameliorate symptoms in major depressive disorder (MDD). In rodents, both are associated with an enhancement of cerebral adenosine levels, which turn likely influence adenosinergic receptor expression. The aim the current study was to investigate A 1 (A AR) availability patients MDD as a potential mediating factor ant...

background: the electrical dose selected for electroconvulsive therapy (ect) must have an acceptable efficacy and no or minimal cognitive side-effects. we evaluated the clinical efficacy and cognitive side-effects of ect in relation to the stimulus dose administered.   method: this study assessed 71 depressed patients who were treated with bilateral ect. for evaluation of depressive and cogniti...

objective: in electrochemotherapy (ect), there is an unpleasant sensation of muscle contraction when using a low frequency (1 hz). therefore, by increasing the pulse frequency above the tetanic frequency this painful sensation can be reduced. the aim of the present study is to compare the treatment efficiencies of low and high frequency ect, and estimate the effect of its repeated sessions. mat...

Anesthesia for electroconvulsive therapy (ECT) usually involves the intravenous (IV) administration of drugs such as methohexital, thiopental, propofol, etomidate, or ketamine. Sevoflurane is an inhalational anesthetic agent that has been available past 3 decades. Although many studies have examined sevoflurane in context ECT, treatment guidelines make either no mention only passing its potenti...