introduction: bombesin (bn), a 14-amino acid neuropeptide, shows high affinity for the human grp (gastrin releasing peptide) receptors, which are overexpressed by a variety of cancers, including prostate, breast, pancreas, gastrointestinal, and small cell lung cancer. aim was to prepare [6-hydrazinopyridine-3-carboxylic acid (hynic0), d-tyr6, d-trp8] - bn [6-14] nh2 that could be easily labeled...

В целях оптимизации микроэлементного обмена животных в биогеохимическом регионе было изучено влияние комплексонатов, приготовленных на основе полидентатной этилендиаминдиянтарной кислоты, рационе овец. спектре эксперимента были изучены следующие показатели: концентрационный фон редуцирующего моносахарида, лактата, пирувата, липидов и липидных фракций сыворотке крови. Результаты показали положит...

A 62-year-old woman diagnosed with a pancreatic neuroendocrine tumor (NET) underwent surgery in 2004 and was reoperated in 2009 for recurrence in the greater curvature of the stomach. Theposterior clinical and radiological controlswerenegative until 2011. InMarch 2011 a somatostatin receptor scintigraphy with 99mTcEDDA/HYNIC-TOC was performed to rule out new recurrence which was suspected due t...

Debris flow material properties change during the initiation, transportation and deposition processes, which influences the runout characteristics of the debris flow. A quasithree-dimensional depth-integrated numerical model, EDDA (Erosion–Deposition Debris flow Analysis), is presented in this paper to simulate debris flow erosion, deposition and induced material property changes. The model con...