background osteoarthritis (oa) is a multifactorial, disabling and degenerative disease that worsens with age and affects patient’s health-related quality of life (hrqol). objectives the current study aimed to assess if age and comorbidities have an influence on knee oa and knee replacement outcome before and after the surgery. methods a quasi-experimental intervention study was conducted on a s...

patients and methods in the double-blind placebo study, 33 obese children with nafld from 2008 to 2009 were included. lifestyle intervention (balanced calorie diet, 1300-1800 kcal/d and physical activity) was prescribed to all. the patients were concurrently randomized to receive vitamin e 400 mg/d (n = 17)] or placebo (n = 16). results at the end of six months of therapy there was significant ...