We used clinically relevant murine allogeneic bone marrow transplantation (BMT) models to study the mechanisms by which IL-7 administration can improve posttransplant peripheral T cell reconstitution. After transplant we could distinguish two populations of mature donor T cells: (a) alloreactive T cells with decreased expression of CD127 (IL-7 receptor alpha chain) and (b) nonalloreactive T cel...

Abstract Up to now, we know only a little about the causal effect of international migration on partnership stability, with few existing analyses being restricted internal or from less developed countries Global North. Using longitudinal data German citizens [the Emigration and Remigration Panel Study plus Family (pairfam)], this study contributes literature primarily in two ways: first, by com...

Fully functional T cells are necessary for the maintenance of protective immunity during chronic infections. However, activated T cells often undergo apoptosis or exhaustion upon chronic stimulation mediated by Ag or inflammation. T cell attrition can be compensated for by the production of thymus-derived T cells, although the new naive T cells must undergo T cell priming and differentiation un...

We have previously shown that conventional as well as germ-free CD4+ T cells depleted of CD25+ cells from the gut-associated lymphoid tissue and the periphery proliferate specifically in response to enterobacterial antigen exposure whereas unfractionated CD4+ T cells are not reactive under these conditions. Here we show that the majority of the enteroantigen-specific CD4+ CD25- T cells are naiv...

Colonial New Zealand was built on the ideal of creating better lives for settlers. Emigrants came looking to escape shackles class system and poor conditions in Industrial Revolution–period Britain. propaganda claimed that most emigrants achieved their aims, but colonists actually experienced upon reaching remain relatively unexplored from a biosocial perspective. In this article we present pil...

What drove an entire region in the Global South to significantly expand refugee protection early twenty-first century? In this paper, we test and build on political theory via a mixed-methods approach explain liberalization of legislation across Latin America. First, use data from new APLA Database, which measures legislative over 30-year period, both general region-specific immigration policy ...

In a country founded by European emigrants, where the migratory flux has never stopped since first settlers arrived in 17th Century, immigration coming from far beyond Río Grande always been considered as invading. Through musicals like West Side Story (1957) and Heights (2007), we will analyze change of paradigm Latino portrait American musical.

Migratory movements have been a recurrent theme of study in the field of Population Geography. In Spain, attention has focused on emigration after the civil war; and on the more recent immigratory movement. The return movement has always been deemed less important, although it is very interesting due to the significance of the emigration to which it is associated. More often than not, macroecon...