The toxicity of endodontic materials is reviewed. The patient may be exposed by constituents leaching from the unset and set sealer and by accidental overfilling of the root canal. For most patients the exposure is believed to be below the threshold for a toxic effect. Most sealers exhibited a cytotoxic response, especially unset and the responses diminished with time after setting. Unset and n...

Contemporary research points to infection control as the key determinant of endodontic success. While epidemiological surveys indicate that success is most likely in teeth which have been densely root-filled to within 2 mm of root-end, it is unclear whether the root canal filling itself is a key determinant of outcome. It is also unclear how different materials and methods employed in achieving...

The purpose of this study was to compare the amount of dye leakage (in the presence versus absence of blood) in root end cavities filled with amalgam, Super EBA, IRM, and a mineral trioxide aggregate. After removing the anatomical crowns of 90 extracted human teeth, their roots were instrumented and obturated. Except for their apical 2 mm, the root surfaces were sealed with nail polish. After r...

OBJECTIVE The purpose of this study was to evaluate the sealing ability of castor oil polymer (COP), mineral trioxide aggregate (MTA) and glass ionomer cement (GIC) as root-end filling materials. Forty-five single-rooted human teeth were cleaned and prepared using a step-back technique. The apical third of each root was resected perpendicularly to the long axis direction. All teeth were obturat...

INTRODUCTION The purpose of this clinical study was to compare the blood mercury levels before and after endodontic surgery using amalgam as a root-end filling material. MATERIALS AND METHODS Fourteen patients requiring periradicular surgery participated in this prospective clinical study. A zinc-free amalgam was employed as root-end filling material. Blood samples were collected at three int...

OBJECTIVES The aim of this study was to evaluate marginal adaptation of mineral trioxide aggregate (MTA), calcium enriched mixture (CEM) cement, Biodentine and BioAggregate in presence of normal saline and human blood. MATERIALS AND METHODS In this in-vitro experimental study, 80 extracted single-rooted human teeth were instrumented and filled with gutta-percha. After resecting the root-end, ...