نتایج جستجو برای: endocannabinoid signaling
تعداد نتایج: 301155 فیلتر نتایج به سال:
Glucocorticoids exert an opposing rapid regulation of glutamate and GABA synaptic inputs to hypothalamic magnocellular neurons via the activation of postsynaptic membrane-associated receptors and the release of retrograde messengers. Glucocorticoids suppress synaptic glutamate release via the retrograde release of endocannabinoids and facilitate synaptic GABA release via an unknown retrograde m...
Inspired by the medicinal properties of plant Cannabis sativa and its principal component (?)- trans-? 9 -tetrahydrocannabinol (THC), researchers have developed a variety compounds to modulate endocannabinoid system in human brain. Inhibitors fatty acid amide hydrolase (FAAH) monoacylglycerol lipase (MAGL), which are enzymes responsible for inactivation endogenous cannabinoids anandamide 2-arac...
Spinocerebellar ataxia type-3 (SCA-3) is the most prevalent autosomal dominant inherited ataxia. We recently found that the endocannabinoid system is altered in the post-mortem cerebellum of SCA-3 patients, and similar results were also found in the cerebellar and brainstem nuclei of a SCA-3 transgenic mouse model. Given that the neuropathology of SCA-3 is not restricted to these two brain regi...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید