Nuclear receptors play important roles in the maintenance of the endocrine system, regulation of organ differentiation, and fetal development. Endocrine disruptors exert their adverse effects by disrupting the endocrine system via various mechanisms. To assess the effects of endocrine disruptors on nuclear receptors, we developed a high-throughput method for identifying activators of nuclear re...

regarding to the important of pancreas in the body, this study was carried out on the histologic structure of pancreas of 6 pairs of iranian native turkeys of both sexes, age ranging from 26-30 weeks. routine histological techniques were used and stained by h&e; and masson’s trichrome, gomori’s method for reticulum, verhoeff’s, maldonado’s methods. the pancreas was covered with a thick dense co...

Mercury (Hg) is well studied and research continues as our knowledge of its health risks increases. One expanding area of research not well emphasized to date is the endocrine effects of Hg. This review summarizes the existing literature on the effects of Hg on the endocrine system and identifies gaps in the knowledge. It focuses on the thyroid, adrenal, and reproductive systems, including the ...

Metastatic cancer may be treated either by excision of endocrine glands (surgical deprivation) or administration of hormones (addition therapy). This article deals only with deprivation. Addition will only be considered as it directly affects deprivation and not as a method of therapy in its own right. The purpose of surgical deprivation is to terminate the production of the specific hormones e...

Endocrine cancers are a heterogeneous group of diseases that may arise from endocrine cells in any gland of the endocrine system. These malignancies may show an aggressive behavior and resistance to the common anticancer therapies. The etiopathogenesis of these tumors remains mostly unknown. The normal embryological development and differentiation of several endocrine glands are regulated by sp...

This paper deals with the role of widespread neuro-immuno-endocrine-endothelial system in sport traumatology. The aim this work is to see if or regular physical activity able reprogram endothelium, advance new concept diffused system, and introduce practice medicine a test fields “Athlete functional evaluation” “Sports fitness”. first object whether can change structure endothelium. second goal...

Spend your few moment to read a book even only few pages. Reading book is not obligation and force for everybody. When you don't want to read, you can get punishment from the publisher. Read a book becomes a choice of your different characteristics. Many people with reading habit will always be enjoyable to read, or on the contrary. For some reasons, this auto immunity in the endocrine system t...

In recent years, nanoparticles have been increasingly used in several industrial, consumer and medical applications because of their unique physico-chemical properties. However, in vitro and in vivo studies have demonstrated that these properties are also closely associated with detrimental health effects. There is a serious lack of information on the potential nanoparticle hazard to human heal...

Ikaros transcription factors are essential regulators of lymphopoiesis and the development of the immune system. We now show that Ikaros is expressed in hormone-producing pituitary corticomelanotroph cells, where it binds the proopiomelanocortin promoter and regulates endogenous gene expression. Loss of Ikaros in vivo results in contraction of the pituitary corticomelanotroph population, reduce...