BACKGROUND The pathogenesis of endometriosis remains poorly defined. The aberrant angiogenesis that occurs in eutopic endometrium may play a role in the lesion formation and survival. The difference in gene expression profile between human endometrial endothelial cells (HEECs) from eutopic endometria of patients with and without endometriosis would be a factor that affects the occurrence of end...

Vascularization, the formation of new blood vessels, is an essential biological process. As the vasculature is involved in various fundamental physiological phenomena and closely related to several human diseases, it is imperative that substantial research is conducted on characterizing the vasculature and its related diseases. A significant evolution has been made to describe the vascularizati...

  Background: AUB is a common cause of women’s referring to gynecologists. Although hysteroscopy is known as the gold standard technique for diagnosing the cause of AUB, sonohysterography is less invasive, and it is performed by general gynecologists. The purpose of this study was to evaluate the diagnostic performance of sonohysterography compared to the results of the endometrial biopsy, guid...

AIM To assess the changes in the angiogenic status of rectal cancer before and after preoperative radiotherapy (RT) using endosonography (ES). MATERIAL AND METHODS Fifty-four patients with rectal cancer were examined by ES before and 6-7 weeks after preoperative RT and . The tumour size, stage, echostructure and vascularization before and after RT were compared. Tumour vascularization was det...

The human endometrium develops new capillaries from existing microvessels, i.e. angiogenesis, which then undergo maturation and remodeling, i.e. investment of microvessels with periendothelial mural cells, into a new vascular network during each menstrual cycle. Improper vascularization of the endometrium may cause implantation failure and infertility. Estrogen and progesterone have pivotal rol...

The endometrial stromal nodule is a benign tumor composed of differentiated endometrial stromal cells arranged as a well circumscribed nodule with smooth non-invasive margins. They are rare neoplasms, diagnosed in most instances by microscopy. Although nodules are benign in nature, hysterectomy is the treatment of choice to enable evaluation of the tumor margins which are well demarcated in...

Background: Despite recent technical improvement in assisted reproductive techniques (ART), the implantation rate per embryo still remains low (15%). The aim of the study is to determine whether the failure of IVF cycle is associated with endometrial thickness on the day of HCG (human chorionic gonadotropin) administration. Materials and Methods: Endometrial thickness of two hundred and seven p...

In this paper, we present a dynamic Bayesian network (DBN) approach to modeling vascularization in engineered tissues. Injuries and diseases can cause significant tissue loss to the degree where the body is unable to heal itself. Tissue engineering aims to replace the lost tissue through use of stem cells and biomaterials. For tissue cells to multiply and migrate, they need to be close to blood...