Endometriosis is a common condition in women of reproductive age. According to several epidemiological studies endometriosis may be associated with increased risk of various malignancies. However, endometriosis-associated malignancy (EAM) is defined by certain histological criteria. About 80 % of EAM have been found in the ovary, whereas 20 % are localized in extragonadal sites like intestine, ...

remains a clinical challenge with many patients left undiagnosed with an estimated average delay of up to 10.4 years [5,810]. Two thirds of women with endometriosis are initially misdiagnosed and almost half are examined by five physicians or more before a correct diagnosis is made [11]. Diagnostic delay is significantly longer in women presenting with pelvic pain in comparison to those present...

OBJECTIVE The purpose is to assess current medical practice in the diagnosis of endometriosis by Brazilian gynecologists. METHODS A Cross-sectional study using questionnaires was sent to all gynecologists of the São Paulo State Ob/Gyn Association. RESULTS A total of 1,660 (31.8%) replies was received. Multiple logistic regression showed that physicians who stated that endometriosis can affe...

BACKGROUND/AIMS Endometriosis is regarded as a complex disese, in which genetic and environmental factors contribute to the disease phenotype. Whether vascular endothelial growth factor (VEGF) -460 C/T and +405 G/C polymorphisms are associated with susceptibility to endometriosis was investigated. PATIENTS AND METHODS Diagnosis of endometriosis was made on the basis of laparoscopic findings. ...

Endometriosis is a common, chronic disease. Patients typically present with pelvic pain, infertility, and/or an adnexal mass. Results from the limited number of studies that have been published indicate that the true prevalence of endometriosis, along with the associated infertility, has been increasing. Debates about infertility management arise from the contradiction between the contraceptive...

Background For patients with severe endometriosis,the spontaneous pregnancy rates have been reported to be near 0 due to extreme distortion of normal pelvic anatomy.Surgery is one of the treatment options;however.f,patients failed to conceive after surgerY,in vitro fertilization(IVF)Is effective.The objective of this retrospective study was to determine the clinicaI characteristics of IVF/intra...

BACKGROUND Endometrium can adhere to autologous peritoneum. This study was undertaken to determine the effect of the menstrual cycle phase and the presence and stage of endometriosis on in-vitro adhesion of endometrium onto autologous peritoneum. METHODS This was performed in an academic medical research centre. Sixty-seven subfertile women with a visually normal pelvis (n = 18) and with biop...

Angiogenin, a potent inducer of angiogenesis, is expressed in human endometrium. This study was performed to compare the expression of angiogenin mRNA level in the eutopic endometrium from women with and without endometriosis. Thirty-two women with advanced stage endometriosis and 29 control women were recruited. Following isolation of total RNA from endometrial tissue and reverse transcription...

Retrograde menstruation is postulated as the initiating event in the histogenesis of endometriosis; however, subsequent steps in the pathogenesis of this common disorder remain poorly characterized. The ip accumulation of activated leukocytes and the infiltration of endometriosis lesions by macrophages and T cells are cytological markers of the inflammatory nature of this syndrome. The apparent...