THE USE OF NONINVASIVE POSItive-pressure ventilation (NPPV) in acute respiratory failure to avoid the need for endotracheal intubation was first reported in the late 1980s by Meduri et al. The apparent successful application of this form of ventilation in this and other case series has led to more intensive scrutiny of this technology in randomized controlled trials. It appears that successful ...

INTRODUCTION To determine whether subjecting patients to 100 ml of additional dead space after a 120-minute weaning trial could predict readiness for extubation. METHODS This was a prospective, non-randomised pilot study in an intensive care unit at a university hospital with 14 beds. It included all non-tracheostomised patients with improvement of the underlying cause of acute respiratory fa...

Background The weaning process is complex and needs to be done carefully. The success of extubation in premature babies is associated with brain maturity and adequate function of the lungs. We aimed to identify the ventilator parameters and clinical conditions related to extubation success and failure in premature infants. Materials and Methods This is anobservational study, analytical and non-...

BACKGROUND After patients recovering from respiratory failure have successfully completed a spontaneous breathing trial (SBT), clinicians must determine whether an artificial airway is still required. We hypothesized that cough strength and the magnitude of endotracheal secretions affect extubation outcomes. METHODS We conducted a prospective study of 91 adult patients treated in medical-card...

Objectives: The aim of this study was to evaluate the effect high-flow nasal cannula (HFNC) after early extubation on children undergoing cardiac surgery. Methods: This randomized controlled clinical trial performed among 92 aged 1 24 months surgery from March 5 August 30, 2020, in a pediatric post-cardiac intensive care unit (ICU). patients were receive either HFNC or conventional oxygen thera...

INTRODUCTION Extubation failure has been associated with poor intensive care unit (ICU) and hospital outcomes in tertiary care medical centers. Given the large proportion of critical care delivered in the community setting, our purpose was to determine the impact of extubation failure on patient outcomes in a community hospital ICU. METHODS A retrospective cohort study was performed using dat...

INTRODUCTION Acute pain is common during the endotracheal extubation period, and is related to complications and adverse outcomes. Patients with delayed extubation after craniotomy are vulnerable to pain and complications of extubation. However, pain control during extubation is still inadequate. Remifentanil, a new opioid with rapid onset and short duration of action, provides adequate analges...

Weaning from MV is the gradual removal of the ventilatory prosthesis, a different process to extubation, which involves removing the endotracheal tube (MacIntyre et al., 2001). The best moment to start weaning depends on multiple factors. Premature exhubation puts the patient at risk of reintubation and airway trauma. However, prolonged weaning exposes individuals to risk of hospital infection ...