Active substance: Baytril 10% oral solution contains, as an active substance, enrofloxacin, a fluoroquinolone carboxylic acid derivative. Fluoroquinolones are concentration dependent antimicrobials that are part of the quinolone group of synthetic antibiotics. It is the halogenated chemical groups (fluorine) that, when compared to quinolones, confer the increased effectiveness of enrofloxacin. ...

The ability of various subsets of poultry intestinal microbiota to protect turkeys from colonization by Campylobacter jejuni was investigated. Community subsets were generated in vivo by inoculation of day-old poults with the cecal contents of a Campylobacter-free adult turkey, followed by treatment with one antimicrobial, either virginiamycin, enrofloxacin, neomycin, or vancomycin. The C. jeju...

The blood biochemical parameters were investigated in a yak (Bos grunniens L) after intravenous administration of 5 mg/kg enrofloxacin. Blood samples were collected from the jugular vein daily for 5 days after the drug administration. Heparinized bloods were collected for mean corpuscular volume (MCV), erythrocyte sedimentation rate (ESR), hemoglubin (Hb) estimation and...

BACKGROUND The (mis)use of fluoroquinolones in the fowl industry has led to an alarming incidence of fluoroquinolone resistance in pathogenic as well as commensal bacteria. Next to simply reducing antimicrobial consumption, optimizing dosage regimens can be regarded as a suitable strategy to reduce antimicrobial resistance development without jeopardizing therapy efficacy and outcome. A first s...

Contamination of food producing animals by veterinary drug residues, particularly quinolones, is an essential issue in food safety that causes increasing concern in consumers. The aim of this study was to investigate the occurrence of enrofloxacin and its main metabolite, ciprofloxacin, in chicken tissue samples slaughtered in Tabriz, Iran. Totally 250 samples including liver, muscle, gizzard, ...

The asymmetric unit of the title compound, C19H23FN3O3 (+)·Cl(-)·2H2O [systematic name: 4-(3-carb-oxy-1-cyclo-propyl-6-fluoro-4-oxo-1,4-di-hydro-quin-o-lin-7-yl)-1-ethyl-piperazin-1-ium chloride dihydrate], consists of two independent monocations of the protonated enrofloxacin, two chloride anions and four water mol-ecules. In the cations, the piperazinium rings adopt chair conformations and th...

The clinical efficacy of enrofloxacin was tested in calves with experimentally induced pneumonic pasteurellosis. A strain of Pasteurella haemolytica, biotype A, serotype 1 (P. haemolytica A1), which had been isolated from an outbreak of pneumonic pasteurellosis in feedlot calves, was used to induce the disease in 24 eight-month-old calves. Each animal received, by intratracheal injection, 6 x 1...

s of papers 29 collected daily and subjected to bioassay for detectable antimicrobial residues in yolk. Antimicrobial residues were not detected during the 7 days of treatment or the subsequent 3 days following cessation of treatment in the control, sulfadimethoxine or tylosin treatment groups. However, detectable residues were observed in eggs derived from enrofloxacintreated hens on days 6,7,...