In order to study the prevalence of enteric pathogens capable of causing infection and disease in the rural communities of Nkonkobe, bacterial isolates were collected from several surface water and groundwater sources used by the community for their daily water needs. By making use of selective culture media and the 20E API kit, presumptive Escherichia coli, Salmonella spp. and Vibrio cholerae ...

BACKGROUND Angiogenesis has been recently described as a novel component of inflammatory bowel disease pathogenesis. The level of vascular endothelial growth factor (VEGF) has been found increased in Crohn's disease and ulcerative colitis mucosa. To question whether a pro-inflammatory Escherichia coli could regulate the expression of VEGF in human intestinal epithelial cells, we examine the res...

stimulate to further effort towards attempting the solution of the many etiological puzzles which, more especially in tropical diseases, still remain unsolved. Among other tropical diseases, the various affections whose leading symptom is intestinal flux, and which are included under the somewhat elastic names of dysentery, sprue, chronic diarrhoea, colitis, entero-colitis, etc., are, perhaps, ...

Crohn's disease (CD) is an intestinal chronic inflammatory disease that can cause damage by contiguity of the urinary tract. Although common form is fistulizing in 35% of patients with CD, the entero-urinary fistulas are rare 2-8%. Diagnosis is based on clinical computed tomographic data. Medical treatment appears to be effective for isolated ileo-vesical fistula, however the association with o...

Escherichia coli O157 is a food borne Shiga toxin-producing human entero pathogenic pathogen known to cause severe diarrhea often accompanied by cramps, nausea, vomiting and slight fever in humans. This bacterium is one of the most aggressive entero hemorrhagic E. coli strains and probably evolved through horizontal transfer of genes encoding for Shiga toxins and other virulence factors. This s...

Porcine Post-Weaning Diarrhea (PWD) continues to be one of the most important swine diseases worldwide. Entero toxigenic Escherichia coli (ETEC) strains are the primary cause of PWD. The key virulence factors of ETEC in PWD are bacterial fimbrial adhesins and enterotoxins. Adhesions mediate ETEC bacteria initial attachment to pig epithelial cells and subsequent colonization at pig small intesti...

The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can affect the consortium dramatically. Antibiotic cessation does not necessarily restore pre-treatment conditions and disturbed microbiota are often susceptibl...