The present study evaluated the in vitro anticataract and antioxidant activities of ethanolic seed extract of Abrus precatorius Linn. (Fabaceae) against calcium-induced cataractogenesis using goat lenses. Transparent isolated goat lenes were incubated in artificial aqueous humor and divided into seven experimental groups. The extracts at a dose of 100 μg/ml and 200 μg/ml were incubated simultan...

OBJECTIVES Hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. In the present study, we evaluated the effect of ethanolic extract of Ensete superbum seeds (ESSE) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. MATERIALS AND METHODS Glucose, HbA1c, total protein, albumin, renal function mark...

The present investigation was an attempt to evaluate the ameliorative effect of curcumin on aflatoxin-induced lipid peroxidation in liver and kidney of mice. Aflatoxin was obtained by growing Aspergillus parasiticus in SMKY liquid medium. Pure curcumin (97% purity) was purchased from Hi-Media Laboratories Pvt. Ltd., Mumbai, India. Young adult male albino mice were orally administered with low d...

Acrylonitrile (ACN) is a volatile, toxic liquid used as a monomer in the manufacture of synthetic rubber, styrene plastics, acrylic fiber and adhesives. ACN is a potent neurotoxin and a carcinogen, which produces tumors in rats, particularly gliomas of the brain. A role for free radical-mediated lipid peroxidation in the toxicity of ACN has been suggested. We examined the ability of taurine, an...

Despite being a plant by-product, chokeberry pomace is believed to exert some therapeutic effects because it is one of the richest sources of highly bioavailable non-enzymatic antioxidants. The aim of this study was to determine the functionality of bioactive compounds present in the Aronia melanocarpa pomace (chokeberry) based on enzymatic and non-enzymatic parameters related to the active def...

The purpose of this study is to determine the relationship between enzymatic antioxidants such as glutathione reductase and s-transferase prolidase adenosine deaminase in patients diagnosed with pancreatic cancer. Prolidase, deaminase, activities were determined spectrophotometrically blood sera collected from healthy control subjects included study. In cancer, mean value enzymes decreased, whi...