Contact networks are often used in epidemiological studies to describe the patterns of interactions within a population. Often, such networks merely indicate which individuals interact, without giving any indication of the strength or intensity of interactions. Here, we use weighted networks, in which every connection has an associated weight, to explore the influence of heterogeneous contact s...

Background: An Ebola outbreak of unparalleled size is currently affecting several countries in West Africa, and international efforts to control the outbreak are underway. However, the efficacy of these interventions, and their likely impact on an Ebola epidemic of this size, is unknown. Forecasting and simulation of these interventions may inform public health efforts. Methods: We use existing...

Despite improved control measures, Ebola remains a serious public health risk in African regions where recurrent outbreaks have been observed since the initial epidemic in 1976. Using epidemic modeling and data from two well-documented Ebola outbreaks (Congo 1995 and Uganda 2000), we estimate the number of secondary cases generated by an index case in the absence of control interventions R0. Ou...

To investigate the impact of weights on the traffic driven epidemic spreading in weighted homogeneous networks, an epidemic model in pseudo-random network with adjustable weights is presented. In the scenario that epidemic pathway is defined and driven by traffic flows, the epidemic spreading velocity of SI model in weighted homogeneous networks is obviously accelerated when the edge weight is ...

Abstract This article analyzes the content related to big data and artificial intelligence technology. The author studied characteristics of COVID-19 epidemic, epidemic characteristics, transmission routes. has use technologies in genome sequencing analysis, intelligent medical diagnostic services, vaccine research development drug screening, reasonable scheduling anti-epidemic resources, monit...

BACKGROUND An Ebola outbreak of unparalleled size is currently affecting several countries in West Africa, and international efforts to control the outbreak are underway. However, the efficacy of these interventions, and their likely impact on an Ebola epidemic of this size, is unknown. Forecasting and simulation of these interventions may inform public health efforts. METHODS We use existing...

This paper is aimed at designing a robust vaccination strategy capable of eradicating an infectious disease from a population regardless of the potential uncertainty in the parameters defining the disease. For this purpose, a control theoretic approach based on a sliding-mode control law is used. Initially, the controller is designed assuming certain knowledge of an upper-bound of the uncertain...

There has been much recent interest in modelling epidemics on networks, particularly in the presence of substantial clustering. Here, we develop pairwise methods to answer questions that are often addressed using epidemic models, in particular: on the basis of potential observations early in an outbreak, what can be predicted about the epidemic outcomes and the levels of intervention necessary ...

The Atlas of Exfoliative Cytology is a valuable distillate of the vast experience of the master cytologist, Dr. George N. Papanicolaou. The doubtless heavy subsidy from the Commonwealth Fund has been well employed. The book has been prepared in all modesty in loose-leaf form "to keep abreast of new advances," and an appeal is made for new material. As befits an atlas, the illustrations are many...

Within 5 years of infection with the virus, 25% of people have developed full blown AIDS and all of them die. The ultimate mortality within 20 years of infection is unknown as the virus has been spreading for only 10 years. Many virologists now accept the pessimistic view that all people infected with the virus will eventually be killed by it. All virologists are agreed that once infected with ...