The aim of the present work was to clarify the anti-melanogenic mechanism of the catechin group. In this study, we used (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin (EGC), (-)-catechin (C), and gallic acid (GA). The catechin group inhibited melanin synthesis in B16 melanoma cells. To elucidate the anti-melanogenic mechanism of the catechin group, we performed Western blotting ana...

[This corrects the article DOI: 10.1371/journal.pone.0112683.].

Clitoria ternatea and Gambir are potential sources of bioactive compounds, but the use leaves has not been widely used as a beverage. This study investigated tea brewed properties from leaves, enriched with butterfly pea extract coloring agent antioxidant enhancer to determine optimal ratio flower tea. completely randomized design, consist 5 treatments three replications. The (GLT) (TF) were 10...

1 Faculty of Health Sciences, Fernando Pessoa University, Porto, Portugal; 2 Centre for Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Vila Real, Portugal, 3 Department of Biology and Environment, University of Trás-os-Montes e Alto Douro (UTAD), Vila Real, Portugal; 4 Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Barcel...

Numerous studies have demonstrated the importance of naturally occurring dietary polyphenols in promoting cardiovascular health and emphasized the significant role these compounds play in limiting the effects of cellular aging. Polyphenols such as resveratrol, epigallocatechin gallate (EGCG), and curcumin have been acknowledged for having beneficial effects on cardiovascular health, while some ...

To figure out the pathway by which epigallocatechin gallate restrains angiogenesis and glycolysis in colorectal cancer through circular ribonucleic acid (actin gamma 2)/microRNA-370-5p axis. Detection of actin 2 microRNA-370-5p patient tissues cells vascular endothelial growth factor A was conducted. Cell viability proliferation, angiogenesis, glucose lactate were examined. Circular microRNA-37...