نتایج جستجو برای: epithelial neoplasia

تعداد نتایج: 180290  

Journal: :Current gastroenterology reports 2012
Michelle H Lee Kristin Buterbaugh Rebecca Richards-Kortum Sharmila Anandasabapathy

Barrett's esophagus is the precursor to esophageal adenocarcinoma, one of the most rapidly increasing cancers in the United States. Given the poor prognosis of late-stage adenocarcinoma, endoscopic surveillance is recommended for subjects with Barrett's esophagus to detect early neoplasia. Current guidelines recommend "random" four-quadrant biopsies taken every 1-2 cm throughout the Barrett's s...

2015
Jared J. Barrott Benjamin E. Illum Huifeng Jin Ju-Fen Zhu Tim Mosbruger Michael J. Monument Kyllie Smith-Fry Matthew G. Cable Yanliang Wang Allie H. Grossmann Mario R. Capecchi Kevin B. Jones

β-catenin is a master regulator in the cellular biology of development and neoplasia. Its dysregulation is implicated as a driver of colorectal carcinogenesis and the epithelial-mesenchymal transition in other cancers. Nuclear β-catenin staining is a poor prognostic sign in synovial sarcoma, the most common soft-tissue sarcoma in adolescents and young adults. We show through genetic experiments...

Journal: :Arquivos brasileiros de oftalmologia 2011
Luiz Filipe de Albuquerque Alves Bruno Franco Fernandes Julia Valdemarin Burnier Pablo Zoroquiain Demian Temponi Eskenazi Miguel Noel Burnier

PURPOSE The purpose of this study was to assess the relative frequency of epithelial lesions of the conjunctiva in Canada. METHODS A retrospective study of 12,102 consecutive cases received during 16 years (1993-2009) at the Henry C. Witelson Ocular Pathology Laboratory in Montreal, Canada, was performed. Demographic data was retrieved from histopathological request forms and specimens were c...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Ji Luo Cassandra L Sobkiw Nicole M Logsdon John M Watt Sabina Signoretti Fionnuala O'Connell Eyoung Shin Youngju Shim Lily Pao Benjamin G Neel Ronald A Depinho Massimo Loda Lewis C Cantley

Mice with heterozygous deletion of the PTEN tumor suppressor gene develop a range of epithelial neoplasia as well as lymphoid hyperplasia. Previous studies suggest that PTEN suppresses tumor formation by acting as a phosphoinositide phosphatase to limit signaling by phosphoinositide 3-kinase (PI3K). Here, we examined the effect of deleting various regulatory subunits of PI3K (p85alpha and p85be...

Journal: :Koloproktologiâ 2023

AIM: to evaluate the pilot program results for colorectal cancer (CRC) screening of Sverdlovsk region (April — October 2021) PATIENTS AND METHODS: a three-stage CRC included at first stage, fecal immunochemical test was performed (patients aged 45–65 years). The second stage questionnaire. According questioning, patients with positive and potential risk underwent colonoscopy third stage. RESULT...

Journal: :Veterinary Record Case Reports 2022

The objective of the study was to describe clinical, imaging, surgical and histological findings in a dog with Rathke's cleft cyst pituitary gland. A 6-year-old, female, neutered Staffordshire bull terrier presented an acute onset abnormal behaviour. Magnetic resonance imaging skull showed mass 12.9 mm (height) × 8.8 (width) 10.2 (length) height/brain area value 0.73 (reference <0.31). were sug...

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