BACKGROUND AND AIM Today, electron accelerators are taken into consideration as photoneutron sources. Therefore, for maximum production of epithermal neutron flux, designing a photoneutron target is of significant importance. In this paper, the effect of thickness and geometric shape of a photoneutron target on neutron output were investigated. METHODS In this study, a pencil photon source wi...

In the current article, we provide in vitro efficacy evaluation of a unique accelerator-based neutron source, constructed at the Budker Institute of Nuclear Physics (Novosibirsk, Russian Federation), for boron neutron capture therapy (BNCT), which is particularly effective in the case of invasive cancers. U251MG, CHO-K1 and V79 cells were incubated and irradiated in various concentrations of bo...

The Neutron Therapy Facility at Fermilab has treated cancer patients since 1976. Since then more than 2,300 patients have been treated and a wealth of clinical information accumulated. The therapeutic neutron beam at Fermilab is produced by bombarding a beryllium target with 66 MeV protons. The resulting continuous neutron spectrum ranges from thermal to 66 MeV in neutron energy. It is clear th...

The research in NANE group is focused on the development of the NAA (Neutron Activation Analysis) methodologies and on their application to environment, nutrition and epidemiology studies. NANE is a multidisciplinary group that has the collaboration of researchers from different fields of science: environment, chemistry, physics, environmental health, biology, biochemistry and geology. The capa...

The objective of this study is to demonstrate the feasibility of constructing a compact neutron detector that is sensitive to thermal and epithermal neutrons and has high rejection efficiency relative to gamma-ray background. A two-channel high-pressure He scintillation detector is considered for the detection of neutrons in coincidence mode. The detector consists of two large avalanche photodi...

Epithermal neutron capture and transmission measurements were performed using the timeof-flight method at the Rensselaer Polytechnic Institute linac using metallic Nb samples. The capture measurements were made at the 25-m flight station with a 16-section sodium iodide multiplicity detector and the transmission measurements at the 25-m flight station with a 6Li glass scintillation detector. Res...

BACKGROUND This work presents an initial proposed design of a Prompt Gamma Activation Analysis (PGAA) facility to be installed at the TRIGA IPR-R1, a 60 years old research reactor of the Centre of Development of Nuclear Technology (CDTN) in Brazil. The basic characteristics of the facility and the results of the neutron flux are presented and discussed. FINDINGS The proposed design is based o...

In 2001, at the TRIGA reactor of the University of Pavia (Italy), a patient suffering from diffuse liver metastases from an adenocarcinoma of the sigmoid was successfully treated by boron neutron capture therapy (BNCT). The procedure involved boron infusion prior to hepatectomy, irradiation of the explanted liver at the thermal column of the reactor, and subsequent reimplantation. A complete re...

in 1960’s, but showed little development, as the thermal and epithermal neutron sources were not economical. Nuclear reactors, and recently cyclotrons are being used as neutron sources, thus enabling its widespread utilization (1). Gamma rays are utilized for the irradiation of tumor tissues, and fractional doses up to 50-60 Gray required for tumor ablation in conventional radiation therapy. Su...