The effects of eicosapentaenoic acid on synthesis and secretion of cholesterol and cholesterol ester by cultured rat hepatocytes were studied. In the presence of eicosapentaenoic acid cellular cholesterol esterification was decreased by 50-75% compared to oleic acid as measured by radioactive precursors and mass. Secretion of cholesterol ester was reduced by 50-60% in the presence of eicosapent...

OBJECTIVE Pulmonary surfactant-associated protein B (SP-B), which is synthesized and secreted by alveolar epithelial type II cells, is crucial for normal functioning of pulmonary surfactant. Degeneration of pulmonary surfactant is the essential cause of acute lung injury (ALI). ALI is often studied in animal models using oleic acid, and the effects of oleic acid on pulmonary surfactant and SP-B...

For determining the fatty acid characteristics and biodiesel quality of Ethiopian Jatropha provenances, the study was conducted in five regions namely Southern Nation Nationalities Peoples Regional State (SNNPRS), Amhara region, Tigria region, Oromia region and Benishangul Gumuz Regions, where physic nut is found abundantly. For each region, representative sampling sites were selected following...

For determining the fatty acid characteristics and biodiesel quality of Ethiopian Jatropha provenances, the study was conducted in five regions namely Southern Nation Nationalities Peoples Regional State (SNNPRS), Amhara region, Tigria region, Oromia region and Benishangul Gumuz Regions, where physic nut is found abundantly. For each region, representative sampling sites were selected following...

The esterification of free fatty acids (FFA) with methanol is studied using Sulfonated Porous Carbon (SPC) as catalyst. In compare to the amorphous sugar catalyst and protonated Nafion, the proposed catalyst shows stability and high efficient performance in biodiesel production. The highest initial rate of oleic acid conversion is obtained at catalyst loading of 1 mmol H+ and mole ra...

Ruminant products are significant sources of dietary trans fatty acids. Trans fatty acids, including various conjugated linoleic acid isomers, have been shown to act as metabolic modifiers of lipid metabolism. Trans fatty acids originate from biohydrogenation of dietary unsaturated fatty acids by gut microbes; however, the exact synthetic pathways are unclear. It was our goal to examine the bio...

Binding of 13C-enriched oleic acid to bovine serum albumin and to three large proteolytic fragments of albumin--two complementary fragments corresponding to the two halves of albumin and one fragment corresponding to the carboxyl-terminal domain--yielded unique patterns of NMR resonances (chemical shifts and relative intensities) that were used to identify the locations of binding of the first ...

Introduction. Edible oils containing > 60 % monoenoic acids (i. e. oleic acid), in particular olive oil and Canola oil have been shown to exhibit beneficial effects on lipid metabolism in human (LDL-cholesterol blood levels, triacylglycerol blood levels) within the last few years [1]. These findings are in contrast to earlier recommandations by nutrition experts who strongly favored high-linole...

Fatty acids are essential components of the dynamic lipid metabolism in cells. Fatty acids can also signal to intracellular pathways to trigger a broad range of cellular responses. Oleic acid is an abundant monounsaturated omega-9 fatty acid that impinges on different biological processes, but the mechanisms of action are not completely understood. Here, we report that oleic acid stimulates the...

The metabolic fate of (14)C-labeled fatty acids which have been incubated with human platelets, has been traced. The following has been shown. (a) Intact platelets have a considerable capacity to oxidize fatty acids. (b) When tracer amounts of four of the most common fatty acids in normal plasma were incubated with platelets, each showed a distinctive pattern of uptake among neutral lipids and ...