We recently synthesized all stereoisomers of 1,10-bisaboladien-3-ol and 10,11-epoxy-1-bisabolen-3-ol, including three stink bug pheromones, via a rhodium-catalyzed asymmetric addition of trimethylaluminum to diastereomeric mixtures of cyclohex-2-enones. However, yields of trans isomers were low, and scaling reactions using expensive catalysts were cumbersome. Now we describe a new synthesis of ...

7-O-Methyl-luteone was metabolized in a buffer solution by resting cells of Botrytis cinerea which is known as a fungus detoxifying prenylated isoflavones into further oxygenated meta­ bolites, and we could isolate an unstable epoxy-intermediate. The epoxy-intermediate was easily cyclized under acidic conditions to yield the corresponding isoflavone with a hydroxychroman part structure (= dihyd...

The article is concerned with hybrid amorphous polymers synthesized basing on epoxy oligomer of diglycide aliphatic ester of polyethylene glycol that was cured by polyethylene polyamine and lithium perchlorate salt. Structural peculiarities of organic-inorganic polymer composites were studied by differential scanning calorimetry, wide-angle X-ray spectra, infrared spectroscopic, scanning electr...

Taspase1 is a threonine protease responsible for cleaving MLL (Mixed-Lineage Leukemia) to achieve proper HOX gene expression. Subsequent studies identified additional Taspase1 substrates including Transcription Factor IIA (TFIIA) and Drosophila HCF. Taspase1 is essential for cell proliferation and is overexpressed in many cancer cell lines. Currently no small molecule inhibitors of this enzyme ...

Polymerization of β-phenyl glutaconic diethyl ester (GE) with various diamines (DA) at 1:2 molar ratios in 1,4dioxane solvent was carried out at reflux temperature. The resultant amino terminated unsaturated oligomers (ATUP) were characterized by elemental analysis, number of terminal amino groups, IR spectral studies, number average molecular weight estimated by non-aqueous conductometric titr...

Vacuum-assisted resin transfer molding (VARTM) processes have been proven to be cost-effective manufacturing techniques for large composite structures. However, their use has been limited to single resin systems. A large variety Of composite structures requires multiple resins to serve different purposes while being integrated into a single structure. Significant environmental cost savings are ...

Stress corrosion experiments were performed on unidirectional ECR-glass/polymer composites with the modified polyester, epoxy and vinyl ester resins for the use in high voltage composite insulator applications. Two types of ECR-glass fibers with low and high seed counts were investigated. The stress corrosion tests were performed in nitric acid under four point bending conditions and the resist...

Stabilization/Solidification technologies reduce the mobility of hazardous and radioactive contaminants in the environment through both physical and chemical processes. Four stabilization/solidification (S/S) processes were used to solidify three sample matrices contaminated with arsenic, chromium (VI), lead, cesium and strontium. These sample matrices were Idaho National Engineering and Enviro...