Introdução: A resistência bacteriana descrita para o grupo ESKAPE é uma problemática considerável a saúde global que resulta em prejuízos sociais, econômicos e principalmente saúde. Objetivos: Descrever os associados à de pacientes internados com complicações da COVID-19 inerentes as coinfecções causadas pelo bacteriano ESKAPE. Metodologia: Trata-se revisão integrativa literatura, buscas dos es...

Conducting polymers, mainly polyaniline (PANI) and polypyrrole (PPY) with positive charges bind to the negatively charged bacterial membrane interfere activities. After this initial electrostatic adherence, conducting polymers might partially penetrate interact other intracellular biomolecules. can form polymer composites metal, metal oxides, nanoscale carbon materials as a new class of antimic...

Multidrug resistance constitutes a threat to the medical achievements of the last 50 years. In this study, we demonstrated the abilities of two de novo engineered cationic antibiotic peptides (eCAPs), WLBU2 and WR12, to overcome resistance from 142 clinical isolates representing the most common multidrug-resistant (MDR) pathogens and to display a lower propensity to select for resistant bacteri...

In bacterial biofilms, high molecular weight, secreted exopolysaccharides can serve as a scaffold to which additional carbohydrates, proteins, lipids, and nucleic acids adhere, forming the matrix of the developing biofilm. Here we report methods to extract and purify high molecular weight (>15 kDa) exopolysaccharides from biofilms of eight human pathogens, including species of Staphylcococcus, ...

In view of the pressing need to identify new antibacterial agents able to combat multidrug-resistant bacteria, we investigated a series of fused selenazolinium derivatives (1-8) regarding their in vitro antimicrobial activities against 25 ESKAPE-pathogen strains. Ebselen was used as reference compound. Most of the selenocompounds demonstrated an excellent in vitro activity against all S. aureus...

The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of sexually transmitted infection gonorrhea. increased emergence gonorrhea infections worldwide, associated with surging resistance to antimicrobial treatments alarming. Antimicrobial (AMR) a global threat health and occur through various molecular mechanisms. This research aims identify therapeutic targets in N. gonor...

Acinetobacter baumannii is one of the ESKAPE pathogens which are leading cause nosocomial infections throughout world. The aim this study to detect role Some Proteins in Resistance imipenem. research included collection 100 different clinical specimens of( urine, burns, and wounds) isolated from patients Al-Diwaniyah Teaching Hospital for period September December 2021. 20 isolates out belongin...