PURPOSE To observe the effects of Prostaglandin E1 (PGE1) on hematoma, perihematomal tissue and the impairment of neurological function in patients with hypertensive intracerebral hemorrhage (HICH). METHODS A total of 40 patients with HICH were enrolled according to the inclusion criteria and randomly divided into two groups: the control group (n=20) and the PGE1 treatment group (n=20). In ea...

74-76 we would like to note the importance of single photon emission tomography (SPET) as a diagnostic tool of nuclear medicine, often better than other anatomical modalities. Anatomical imaging methods , especially computerized tomography (CT) and magnetic resonance imaging (MRI) are helpful in the diagnosis of acute traumatic brain injuries (ATBI) [1]; however they are not as efficient as SPE...

This study aims to characterize and compare functional brain single photon emission tomography (SPECT) perfusion and connectivity in treatment-resistant depression (TRD) according to distinct demographic or clinical profiles (male vs. female; old vs. young; unipolar vs. bipolar) and to study their relationship to the severity and the duration of episode/illness. We retrospectively included 127 ...

Previous studies of brain single-photon emission tomography (SPECT) showed changes of regional cerebral blood flow (rCBF) in migraineurs during prodromes or headache attacks. Little is known about how successful medication of migraine prevention can reflect rCBF in migraineurs. We highlighted alternation of brain SPECT findings in a migraineur with aura before and after prophylactic treatment w...

AIMS Although there have been no conclusive pathophysiological findings in support of the degeneration theory in the etiology of schizophrenia to date, results of our neuroimaging studies suggest functional changes in the brains of schizophrenics. We evaluated age-related changes of brain perfusion in medicated patients with schizophrenia. METHOD In this study, we evaluated age-related change...

OBJECTIVE The early diagnosis and treatment of cognitive impairment in cirrhotic patients is needed to improve the patients' daily living. In this study, alterations of regional cerebral blood flow (rCBF) were evaluated in cirrhotic patients using statistical parametric mapping (SPM). The relationships between rCBF and neuropsychological test, severity of disease and biochemical data were also ...

The prefrontal cortex is asymmetric in both structure and function. In normal subjects, the right prefrontal cortex is activated more than the left during response inhibition. Patients with attention deficit hyperactivity disorder (ADHD) have impaired response inhibition and altered structural interhemispheric asymmetry. This study was conducted to examine the functional interhemispheric asymme...

A 47-year-old man presented with carotid rete mirabile manifesting as subarachnoid hemorrhage (SAH). Computed tomography showed SAH, and angiography disclosed an abnormal vascular network around the petrous and cavernous portions of the internal carotid artery. Single photon emission computed tomography (SPECT) with technetium-99m methyl cysteinate dimer revealed reduced regional cerebral blood...

UNLABELLED BACKGROUND Several algorithms from the literature were compared with the original random walk (RW) algorithm for brain perfusion heterogeneity quantification purposes. Algorithms are compared on a set of 210 brain single photon emission computed tomography (SPECT) simulations and 40 patient exams. METHODS Five algorithms were tested on numerical phantoms. The numerical anthropom...

BACKGROUND It remains to be elucidated whether brain activity is altered in takotsubo cardiomyopathy. METHODS AND RESULTS We measured cerebral blood flow (CBF) in 3 consecutive patients with takotsubo cardiomyopathy using (99m)Tc ethyl cysteinate dimmer single photon-emission computed tomography (SPECT) in the acute and chronic phases. In all patients, CBF was significantly increased in the h...