Aldehyde dextran sulfonate (ADS), a modified oligosaccharide polymer, was used to prepare a new matrix structure for affinity biosensors. The principal difference between the ADS matrix and similar structures developed previously results from presence of two active functional groups in the matrix, namely, aldehyde and sulfonate. These groups perform two different functions in the matrix. The al...

The protective effect of olive mill pomace (OMP) loaded ethylcellulose microparticles as an alternative to synthetic antioxidants against the oxidation oils was assessed. OMP extract obtained by optimized two-step solid-liquid extraction; encapsulation performed double emulsion solvent evaporation technique considering a theoretical loading content in phenolic compounds 5% (w/w). changes peroxi...

Natamycin, an antifungal agent that has been approved in the management of exteriorfungal infectionsof oculus such asfungal keratitis,blepharitis, and conjunctivitis. The ophthalmic preparation needs frequent installation into eye due to quickprecorneldrugloss which may lead poor bioavailability. present investigation aimed at formulation development characterization situophthalmic gel natamyci...

The present work was performed with the objective of novel topical formulation development poorly water-soluble drug Diclofenac diethylamine by loading drug-containing nanosponge into formulation. nanosponges are polymeric nanoparticles that entrap drug. drug-loaded has different absorption characteristics in comparison to pure delivery system. Methods: first loaded ethylcellulose using emulsio...