BACKGROUND The American Cancer Society (ACS) guidelines for screening with breast magnetic resonance imaging (MRI) recommend MRI for women who have a lifetime risk > or = 20% of developing breast cancer. Genetic testing for breast cancer gene (BRCA) mutations is offered to women who have a risk > or = 10% of carrying a mutation. The objectives of the current study were 1) to identify the number...

BACKGROUND The excess risk of bilateral visual impairment (BVI; bilateral visual acuity <0.5) among individuals with amblyopia is an argument for screening for amblyopia, but data are scarce. METHODS The risk was estimated by determining the incidence of BVI in the Rotterdam Study, a population-based cohort of subjects aged 55 years or over (n = 5220), including 192 individuals with amblyopia...

abstract background: breast cancer is the most prevalent cancer among iranian women, and is the fifth cause of cancer-related death in iran. most studies have reported an overall excess of 20–30% chance for a second primary cancer to develop in individuals with a first breast cancer. in this study, we evaluated different factors might have a role in increasing the incidence of a second malignan...

Background: Human activities such as mining enhance the radioactivity levels above normal background which can lead to an incremental increase in the radiation risk to the population. Materials and Methods: 20 tailing enriched soil samples collected around Maiganga coal mine, Gombe, Northeast Nigeria were assessed for their 226Ra, 232Th and 40K contents using HPGe gamma-ray detector. Results: T...

background: attempts for early detection of gastric cancer have recently focused on host&apos;s genetic susceptibility factors and gene-environment interactions. we have, herein, studied the association of mthfr c677t single nucleotide polymorphism (snp) and its interaction with helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an iranian population. met...

introduction artificial and natural radionuclides are found in diverse environmental compartments, such as water, soil, rocks, vegetables, animals, and human body tissues. as such, humans and environments are at constant exposure of these radiation types. in this research investigated specific activities of radionuclide and dose assessment of some species of mushrooms. materials and methods in ...

This study presents the results of ambient radioactive radiation, radiation health hazard indices and excess lifetime cancer risk estimation around radiological sections in Federal Teaching Hospital Gombe, Gombe State, Nigeria using a well calibrated Rados-200 meters Global Positioning System (Garmin 765). The mean annual outdoor equivalent dose 0.078 mSv/y. was measured. Mean effective doses 0...

The mortality patterns of United Kingdom tin miners were examined in relation to calendar period and duration of underground work with particular attention to lung cancer and exposure to radon. Subjects were all men who had worked for at least one year between 1941 and 1984 at one of two United Kingdom tin mines and for whom a complete work history could be constructed from mine records. Standa...