The efficiency and accuracy are usually regarded as two general indices to check capability of a numerical method with respect to the time integration. The traditional numerical manifold method (NMM) employs implicit scheme to obtain high computational accuracy, but the efficiency is relatively low, especially when the iterations of contacts are involved. In this paper, the temporal coupled exp...

Previous researchers have argued that objects associated with a protagonist may be or held active, in memory. This study expanded on previous work by foregrounded, to investigate the ef1ècts of protagonist association using an inconsistency paradigm on object accessibilìty. Readers experienced more processing diffrculty when a target sentence contradicted previously presented information about ...

The purpose of this paper is to address a question concerning risk management in continuing, multi-party, contractual, clearing and settlement arrangements through which large-value payments are typically made. We are particularly interested in the issues of incentive compatibility when a third party possesses a private information concerning the riskiness of transfers being made. If a third pa...


 Fatal familial insomia (FFI) is a dominant autosomal genetic prion disease characterised by progressive sleep impairment, autonomic nervous system disorders and motor symptoms associated with significant loss of nerve cells in the medial thalamic nuclei.
 Making diagnosis FFI requires presence certain or probable recognised first-degree relative patient, together neuropsychiatric pr...

OBJECTIVE The aim of this study was to evaluate the efficacy of myofascial therapy involving ischemic compression on trigger points in combination with mobilization therapy on patients with chronic nonspecific foot pain. STUDY DESIGN Two quasi-experimental before-and-after studies involving two different baseline states. METHOD Foot pain patients at a private clinic were divided into two se...

BACKGROUND Accurately measuring, reporting and comparing outcomes is essential for improving health care delivery. Current challenges with available health status scales include patient fatigue, floor/ceiling effects and validity/reliability. METHODS This study compared Patient Reported Outcomes Measurement Information System (PROMIS)-based Lower Extremity Physical Function Computerized Adapt...

Genetic prion diseases are degenerative brain disorders caused by mutations in the gene encoding the prion protein (PrP). Different PrP mutations cause different diseases, including Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker (GSS) syndrome and fatal familial insomnia (FFI). The reason for this variability is not known. It has been suggested that prion strains with unique se...

Aim: The present study aimed to examine the predictors of comorbid psychological symptoms in social anxiety disorder (SAD) after cognitive-behavioral therapy (CBT). Methods: One hundred fourteen SAD patients completed manualized group CBT. We examined associations between the personality dimensions of NEO Five Factor Index (NEO-FFI) and the subscales of Symptom Checklist-90 Revised (SCL-90-R) i...

BACKGROUND Fatal familial insomnia (FFI) is a rare autosomal dominant disease caused by the PRNP D178N/129 M mutation. Routine brain CT and MRI usually reveal non-specific features. We report a patient with FFI presenting with diffuse abnormal signals on MRI, later confirmed as combined with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). ...