The equivalence of processes is an important constituent of process optimization. The article considers the functional equivalence problem for processes in object-oriented environments for the case when the turn of executing operations for different objects is not essential. It is shown that this problem can be reduced to the equivalence problem of regular expressions over a partially commutati...

Selectivity estimation of path expressions in querying XML data plays an important role in query optimization. A path expression may contain multiple branches with predicates, each of which having its impact on the selectivity of the entire query. In this paper, we propose a novel method based on 2-dimensional value histograms to estimate the selectivity of path expressions embedded with predic...

The work investigates the general suitability of purpose of abstract evolutionary approaches by investigating the issues involved with re-factoring an existing, gene expression programming based, drone control system into an immunologically based general purpose optimization system. The re-purposed model is investigated regarding its suitability suitable for use in clonal expansion based optimi...

It is generally assumed that stabilizing selection promoting a phenotypic optimum acts to shape variation in quantitative traits across individuals and species. Although gene expression represents an intensively studied molecular phenotype, the extent to which stabilizing selection limits divergence in gene expression remains contentious. In this study, we present a theoretical framework for th...

I acid is an important building block for the chemical industry. Currently, Aspergillus terreus is the main organism used for itaconic acid production. Due to the enormous citric acid production capacity of Aspergillus niger, this host is investigated as a potential itaconic acid production host. Several strategies have been tried so far: fermentation optimization, expression of cis-aconitate d...

In term of Compiler optimization, classical compilers implemented with an effective optimization technique called Peephole optimization. In the early stage of the implementation of this technique basically applied using string pattern matching performed on the regular expression and which are known as classical peephole optimizers. In the classical optimizers, the string pattern matching approa...

Pigment epithelium-derived factor (PEDF) is widely known for its neurotrophic and antiangiogenic functions. Efficacy studies of PEDF in animal models are limited because of poor heterologous protein yields. Here, we redesigned the human PEDF gene to preferentially match codon frequencies of E coli without altering the amino acid sequence. Following de novo synthesis, codon optimized PEDF (coPED...

background: transient gene expression (tge) gained popularity over the last decade as a rapid method for the production of milligram to gram quantities of recombinant proteins for preclinical studies in biophama industry. thereby, the optimization of the tge technique for chinese hamster ovary (cho) as the dominant host for the production of biotherapeutics is of great interest to reach the val...

This paper deals with an approach to the optimization of enterprise information system(EIS) based on the object-based knowledge mesh (OKM) and binary tree. Firstly, to explore the optimization of EIS by the user’s function requirements, an OKM expression representation based on the user’s satisfaction and binary tree is proposed. Secondly, based on the definitions of the fuzzy function-satisfac...

conclusions these findings of the present study indicate that the recombinant coree1e2 glycoprotein is effective in inducing neutralizing antibodies, and is an influential hcv vaccine candidate. results in our study, the virus-like particle of rcoree1e2 with 70 nm size, was shown by electron microscopy and proved the self-assembly in vitro in a yeast expression system. materials and methods by ...