BACKGROUND Tuberculosis kills five lakh patients every year in India, commonest being pulmonary tuberculosis and is often associated with effusion. Delay in diagnosis and treatment results in poor prognosis. Several studies have suggested the role of adenosine deaminase (ADA) in the diagnosis of tuberculous pleural effusions, but false-positive results from lymphocytic effusions have also been ...

PURPOSE To evaluate the impact of intravitreal bevacizumab combined with laser vascular ablation in the management of advanced Coats' disease presenting with exudative retinal detachment. METHODS This was a retrospective review of 24 children that presented with exudative retinal detachments associated with advanced Coats' disease. Mean patient age was 62 months (range 9-160 months). Presenti...

Exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) share similar abnormal choroidal vasculature, but responses to treatments are different. In this study, we sequenced the whole HTRA1 gene and its promoter by direct sequencing in a Hong Kong Chinese PCV cohort. We identified rs11200638, c.34delCinsTCCT, c.59C>T, rs1049331 and rs2293870 significantly ass...

PURPOSE To evaluate the birefringence properties of eyes with age-related macular degeneration (AMD). To compare the information from two techniques--scanning laser polarimetry (GDx) and polarization-sensitive spectral-domain optical coherence tomography (OCT)--and investigate how they complement each other. METHODS The authors prospectively examined the eyes of two healthy subjects and 13 pa...

BACKGROUND Differentiation between exudative and transudative pleural effusions is the initial step in assessment of pleural effusion. The aim of this study was to determine whether high sensitivity C-reactive protein (hsCRP) and tumor necrosis factor α (TNFα) are diagnostic utilities for exudative pleural effusion. METHODS This experimental study assessed 79 patients with pleural effusion wh...

The present study was designed to examine the anatomical parameters of the cardiopulmonary system, the function of venous blood gas parameters and the development of ascites incidence in two genetic line chickens. Three hundred forty day-old chickens from two pure broiler breeder lines, which were different in their growth rate and susceptibility to ascites syndrome were obtained. The relative ...

Abstract Introduction: Adrenal infections are rare, with the Mycobacterium tuberculosis (MTB) being most common causative agent in developing world. MTB usually spreads to adrenal glands hematogenously where it may be clinically manifested years after systemic infection. Here, we present a case of bilateral infection associated peritonitis. Case Presentation: A 46-year-old male, from Ecuador, w...

BACKGROUND Age-related macular degeneration (AMD) is the leading cause of blindness in people aged 65 years and older in developed countries. The pathogenesis of AMD has been linked to mechanisms involving inflammation, oxidative stress, and basal laminar deposit formation between retinal pigment epithelium (RPE) cells and the basal membrane, caused by advanced glycation end products (AGEs). AG...