retinoblastoma is the most common primary intraocular malignancy in childhood. enucleation remains the treatment of choice in many children because the eye can not be salvaged with any other treatment modality. in some cases after enucleation etiologies other than retinoblastoma are detected in histopathologic review (pseudoretinoblastomas). this study aims to evaluate the prevalence and etiolo...

PURPOSE Retinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option. Here, we performed alternate systemic chemotherapy and IAC and retrospectively reviewed the efficacy and safety of this approach. METHODS Patients diagnosed with intra...

We report herein an unusual case of diffuse infiltrating retinoblastoma involving the brain, which caused a patient's death 27 months after enucleation. An eight-year-old boy complained of blurred vision in his right eye (OD) in October 2006. Funduscopic examination showed optic disc swelling, dense whitish vitreous opacity, and an orange-colored subretinal elevated lesion adjacent to the optic...

BACKGROUND Mycotic ocular infections caused by the Scedosporium apiospermum species complex are challenging to treat because of the delayed diagnoses and poor responses to antifungal drugs and surgical treatment. CASE REPORT A case of a 69-year-old male patient with a history of diabetes mellitus type 2 and prior surgery on the right femur is described. In the 10 days prior to the ophthalmic ...

The loss or disfigurement of a body parts specially that pertaining to the face has a deep psychological and social impact on the patient. After enucleation, evisceration or exteneration of the eye, the aim of an ocular prosthesis should be to restore the natural appearance, install confidence and a sense social acceptability in the patient. Custom made prosthesis has several advantages over th...

BACKGROUND Retinoblastoma is a highly malignant tumor of the eye that manifests most often in the first 3 years of life. METHODS Published articles were reviewed to evaluate the clinical features and current methods of diagnosis and to assess the trends in management. RESULTS This malignancy leads to metastatic disease and death in 50% of children worldwide but in less than 5% of children i...

PURPOSE To review the frequency and cause of traumatic enucleation at the University of Wisconsin. METHODS A 12-year retrospective chart review (2000-2012) from the University of Wisconsin Hospital and Clinics of patients who underwent enucleation following ocular trauma with specimens submitted to the University of Wisconsin Eye Pathology Laboratory. RESULTS A total of 188 eyes enucleated ...

Planarians can propagate asexually by fission and successive regeneration. During head regeneration, they again form a new pair of eyes, and sometimes supernumerary eyes. The positions of normal and supernumerary eyes and their regeneration abilities are expected to be highly relevant to the question of where and how the field to regenerate eyes is determined. In this study, spontaneously gener...