PURPOSE Lens epithelium-derived growth factor (LEDGF) is upregulated in response to stress and enhances the survival of neurons in the retina and optic nerve, as well as a wide range of other cells, such as fibroblasts and keratinocytes. Photoreceptor protection was investigated in the RCS rat retinal degeneration model after Ledgf delivery with an adeno-associated virus (AAV) and the mechanism...

UNLABELLED Wearing contact lenses has been identified as a risk factor for the development of eye conditions such as giant papillary conjunctivitis and keratitis. We hypothesized that wearing contact lenses is associated with changes in the ocular microbiota. We compared the bacterial communities of the conjunctiva and skin under the eye from 58 subjects and analyzed samples from 20 subjects (9...

In April 2011, the International Commission on Radiological Protection issued a statement on reduction of the equivalent dose limits for the lens of the eye, and strongly recommended its consideration in the revision of the International Atomic Energy Agency's International Basic Safety Standards on Radiation Protection. The reduced dose limit was incorporated in the final version of the Basic ...

background: most preclinical studies are carried out on mice. for internal dose  assessment of a mouse, specific absorbed fraction (saf) values play an important role.  in most studies, saf values are estimated using older standard human organ compositions  and values for limited source target pairs. objective: saf values for monoenergetic photons of energies 15, 50, 100, 500,  1000 and 4000 ke...

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A retrospective study of 245 fellow eyes of patients admitted in primary acute angle-closure glaucoma (ACG) is presented. Twenty-five (10.2%) had acute ACG in the fellow eye on presentation. Of the remaining 220, 33 (15%) subsequently developed acute ACG before prophylactic surgery was performed. Possible predisposing factors were analysed. The main findings were that acute ACG in the fellow ey...