نتایج جستجو برای: factor v deficiency

تعداد نتایج: 1240345  

Journal: :The Journal of clinical investigation 1974
A S Weiss J I Gallin A P Kaplan

Fletcher factor-deficient plasma is deficient in prekallikrein and therefore generates no bradykinin upon activation with kaolin. It also possesses a diminished rate of kaolin-activable coagulation and fibrinolysis and possesses a defect in kaolin-activable chemotactic activity. These abnormalities are also corrected by reconstitution with purified prekallikrein. Addition of intact activated Ha...

Journal: :Archives of disease in childhood 1980
S J Machin M R Winter S C Davies I J Mackie

An infant with a severe deficiency of factor X presened in the neonatal period with uncontrollable bleeding from heel prick sites, spontaneous bruising, and haematoma. The deficiency was controlled by infusions of dried human factors II, IX, and X concentrate; the half-life of the infused factor X material is only 18 hours. Despite prophylactic weekly infusions of factor X concentrate, the chil...

Journal: :Blood 2000
H L Janssen J R Meinardi F P Vleggaar S H van Uum E B Haagsma F J van Der Meer J van Hattum R A Chamuleau R P Adang J P Vandenbroucke B van Hoek F R Rosendaal

In a collaborative multicenter case-control study, we investigated the effect of factor V Leiden mutation, prothrombin gene mutation, and inherited deficiencies of protein C, protein S, and antithrombin on the risk of Budd-Chiari syndrome (BCS) and portal vein thrombosis (PVT). We compared 43 BCS patients and 92 PVT patients with 474 population-based controls. The relative risk of BCS was 11.3 ...

Journal: :iranian journal of pharmaceutical research 0
majid naderi genetic research center in non-communicable disease, zahedan university of medical sciences mehran karimi hematology research center, shiraz university of medicalsciences, shiraz, iran maryam sadat hosseini department of hematology, allied medical school, tehran university of medical sciences, tehran, iran eshagh moradi affiliation mortea shamsizadeh affiliation akbar dorgalaleh department of hematology, allied medical school, tehran university of medical sciences, tehran, iran

factor xiii deficiency (fxiiid) is an extremely rare hemorrhagic disorder with a prevalence of 1/3-5 million. management of disease is performed by fresh frozen plasma (ffp), cryoprecipitate (cp) or fxiii concentrate (fibrogammin p®). our objective was to assess safety and effectiveness of fibrogammin p® in patients with fxiiid. for this purpose we designed this long-term follow up study on a l...

Journal: :gene, cell and tissue 0
ebrahim miri-moghaddam genetics of non-communicable disease research center, zahedan university of medical sciences, zahedan, ir iran; department of genetics, zahedan university of medical sciences, zahedan, ir iran yasaman garmie department of biology, faculty of science, sistan and balouchestan university, zahedan, ir iran majid naderi genetics of non-communicable disease research center, zahedan university of medical sciences, zahedan, ir iran; genetics of non-communicable disease research center, ali-asghar hospital, azadi ave., zahedan, ir iran. tel: +98-5413414567, fax: +98-5413218998

background congenital factor xiii (fxiii) deficiency is a rare severs autosomal recessive bleeding disorder. objectives the aim of the study was to determine the c559t > c fxiiia genotype frequency in patients with fxiii hemophilia who lived in sistan and balouchestan province in southeast of iran. patients and methods we determined the genotype of 180 patients with factor xiii hemophilia by te...

Journal: :Journal of clinical pathology 1954
J S JENKINS

Of recent years it has become apparent that Quick's one-stage prothrombin time, although a most useful routine laboratory test, does not specifically measure plasma prothrombin. Quick himself (1947) recognized that deficiency of his labile factor (Factor V) caused lengthening of the prothrombin time, and Owren (1947) reported the first case of congenital deficiency of Factor V causing a haemorr...

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