The purpose of this study was to compare the time to failure and muscle activation of young and old adults for a sustained isometric submaximal contraction with the dorsiflexor muscles when the foot was restrained to a force transducer (force-control task) compared with supporting an equivalent inertial load unrestrained in the sagittal plane (position-control task). Seventeen young (23.6+/-6.5...

Dental implants are placed endosseously, and the bone is the ultimate bearer of the occlusal load. Patients are not uniform in the maximum bite force they can generate. The occlusal biting load in the posterior jaw is usually about three times of that found in the anterior. It is possible for supporting implants to be overloaded by the patients' biting force, resulting in bone loss and failure ...

Hereditary Canine Spinal Muscular Atrophy (HCSMA) is an autosomal dominant disorder of motor neurons that shares features with human motor neuron disease. In animals exhibiting the accelerated phenotype (homozygotes), we demonstrated previously that many motor units exhibit functional deficits that likely reflect underlying deficits in neurotrans-mission. The drug 4-aminopyridine (4AP) blocks v...

4. Hunt SA, AbrahamWT, Chin MH, et al; American College of Cardiology; American Heart Association Task Force on Practice Guidelines; American College of Chest Physicians; International Society for Heart and Lung Transplantation; Heart Rhythm Society. ACC/AHA 2005 Guideline Update for the Diagnosis andManagement of Chronic Heart Failure in the Adult: a report of the American College of Cardiolog...

OBJECTIVE To improve the prediction of fractures in dogs with bone tumors of the distal radius by identifying computed tomography (CT) indices that correlate with antebrachial bone strength and fracture location. STUDY DESIGN Prospective experimental study. ANIMALS Dogs with antebrachial osteosarcoma (n = 10), and normal cadaver bones (n=9). METHODS Antebrachia were imaged with quantitati...

RATIONALE Hypercapnic respiratory failure because of inspiratory muscle weakness is the most important cause of death in chronic obstructive pulmonary disease (COPD). However, the pathophysiology of failure of the diaphragm to generate force in COPD is in part unclear. OBJECTIVES The present study investigated contractile function and myosin heavy chain content of diaphragm muscle single fibe...

The plastic deformation and ductile failure behaviors of anisotropic AISI 1018 low carbon steel C260 Cu-Zn brass under uniaxial tensile loading were investigated. full-filed surface U-notched sheet metal was measured by digital image correlation technique. Three-dimensional finite element modeling using the Hill model calibrated post-necking strain hardening curve performed to obtain force hist...

In this paper, an experimental investigation on ultrasonic welding of polyamide composites reinforced with glass fiber has been carried out. The effect of ultrasonic welding parameters, such as welding time, air pressure, hold time and the amount of glass fiber in the composite on tensile strength of weld joints were determined using response surface methodology. This methodology was applied fo...

Transmembrane potentials and isometric force were recorded in right ventricular muscles from cats with right ventricular failure 3-127 days after chronic partial pulmonary artery obstruction. For the majority of failed muscles (at 36°C, 30 stimuli/ min), resting potential, action potential overshoot, action potential maximum rate of rise, isometric active force at optimal length (Po), and dP/dt...