We report a three-phase bone scintigraphy for the diagnosis of a peripheral bone lesion caused by systemic sarcoidosis. A 32-year-old man with suspected osteomyelitis of the right forefinger underwent three-phase bone scintigraphy with Tc-99m hydroxymethylene diphosphonate (HMDP) and single-photon emission computed tomography/computed tomography (SPECT/CT). The lesion was rich in blood flow acc...

Pyrexia of unknown origin (PUO) is a common problem in day-to-day practice. FDG PET CT is an established investigation that aids in identifying the cause of PUO. Due to its high sensitivity PET detects an occult hypermetabolic focus in the body where CT helps in anatomical localization, vascularity, enhancement characteristics of the lesion detected on PET. It helps to differentiate benign vers...

background sarcoidosis is a multisystem disease affecting different organs with different frequency rates depending on geographical location. musculoskeletal abnormalities includes osseous lesions (small and large bone sarcoidosis), sarcoidal arthropathy, and sarcoidal myopathy. musculoskeletal involvement is reported in a significant number of patients. objectives this study aimed to determine...

Sarcoidosis and foreign body reactions are common differential diagnoses of skin granuloma formation. We report a 40 year –old man with sarcoid type granulomas containing polarized foreign materials, and also bilateral hilar adenopathy. It appears that detection of foreign bodies in histopatologic studies of granulomas does not necessarily exclude the possibility of sarcoidosis.

Sarcoidosis is autoimmune disease known from century whose exact etiology is still under debate. Sarcoidosis is a chronic disease and numbers of infections have been reported in sarcoidosis patients. Some of the infections are more commonly reported while other are rarely reported in sarcoidosis. In this paper, we try to review opportunistic infections in sarcoidosis if there are any particular...

familial defective apolipoprotein (apo) b 100 (fdb) causes early-onset coronary heart diseases (chd). it is produced by r3500q mutation of the apob gene resulting in decreased binding of ldl to ldl receptor. we screened the apo b gene for r3500q mutation in 130 hypercholesterolemic patients, among whom 30 patients met criteria of familial hypercholesterolemia (fh). the prevalence of r3500q alle...

INTRODUCTION A Case Control Etiology of Sarcoidosis Study (ACCESS) sarcoidosis organ assessment instrument has been used for more than a decade to establish uniform standards for the probability of sarcoidosis organ involvement. The ACCESS instrument has become increasingly outdated as new technologies have been developed. Furthermore, the ACCESS instrument failed to address all possible organs...

Introduction: Sarcoidosis is a systemic non-caseating granulomatous disorder of unknown etiology that may affect multiple organ systems. Head and neck involvement can present in unusual often nonspecific ways. Observations : We report three cases sarcoidosis with orofacial manifestations: one African American patient an existing diagnosis who presented perioral cutaneous by sarcoidosis, two Cau...