Two in one--We show here that the highly strained trans,trans-diolefin (E,E)-1,5-cyclooctadiene can perform efficiently two different click reactions at fast reaction rates. It is capable of first undergoing [3+2] cycloadditions with 1,3-dipoles at a reaction rate comparable to that of strained cyclooctynes. The resulting cycloadduct can then perform a much faster inverse-electron-demand Diels-...

Reactor and reaction engineering play a vital role in petroleum and chemical processing. The aim of this article is to acquaint the reader with the interaction between reactor design=selection and the characteristics of the chemical reaction of interest. Reactor selection and design are the basis of economical and safe operation. Chemical reactions in petroleum refining include a huge spectrum ...

Chemical reactions are described by edge relabeling graph transformation rules, in which a substrate chemical graph is transformed into a product chemical graph by breaking existing bonds and creating new bonds between atoms. These edge relabeling graph transformation rules are themselves chemical graphs, where the order of a bond before the chemical reaction is distinguished from the order of ...

a novel algorithm for the fast detection of hubs in chemical networks is presented. thealgorithm identifies a set of nodes in the network as most significant, aimed to be the mosteffective points of distribution for fast, widespread coverage throughout the system. we showthat our hubs have in general greater closeness centrality and betweenness centrality thanvertices with maximal degree, while...