To obtain immature fat cells in vitro, we used a primary culture of undigested mature fat tissue fragments. The immature fat cells, i.e., fibroblast-like fat cells, proliferated extensively from the fat tissue and differentiated after reaching confluence. The process of differentiation was assumed by the development of intracytoplasmic lipid droplets and by the triglyceride content in the cells...

The purpose of the present work was to study age- and weight-controlled rats to determine which is the primary factor in reducing the lipolytic response of free fat cells and which has the greater effect on the ratio of fat cells to nonfat cells in adipose tissue. The method for estimating fat cell and nonfat cell numbers is based on the analysis of adipose tissue and fat cell DNA and lipid. In...

Introduction The recent epidemic rise in metabolic syndrome/insulin resistance and type 2 diabetes are considered to be a result of a sedentary lifestyle combined with a high caloric diet. Earlier reports have consistently shown a link between a high fat intake, especially saturated fat, and insulin resistance [1]. More recently, the intake of simple carbohydrates, especially fructose, have bee...

Investigating the adipose tissue surrounding heart and large vessels, so-called pericardial fat, is of great interest for researchers. Pericardial fat currently being considered a new cardiovascular risk factor, which forces us to reconsider pathogenesis various disorders. The article describes concept including its heterogeneous structure origin determining functional role. In addition, specif...

Introduction: Type 2 diabetes mellitus (T2DM) is a non-communicable disease with high prevalence in Indonesia. T2DM caused by insulin resistance and relative deficiency. One of the therapy for administration which injected into subcutaneous tissue. The absorption tissue influenced many factors, one thickness fat. This study aimed to determine correlation between skinfold patients total daily do...

objective: visfatin, is a novel adipokine, and an adipose tissue-derived hormone shown to correlate with visceral fat mass in patients with obesity. it is not well known whether endurance training – induced change in adipose tissue and blood lipids decreases plasma visfatin or not; thus, the purpose of this study was to examine the effect of 12 weeks endurance training on plasma visfatin in men...

The effects of addition of adipose tissue, rendered fat, rendered fat + the separated connective tissue and rendered fat + gelatin, respectively, were compared on the fat-holding properties of hamburgers upon heating. The fat losses on frying (175 °C, 3.5 minutes on each side) were substantially less than in the net test (cooking in a water bath at 77 oc for 35 minutes, followed by a centrifuga...

Familial partial lipodystrophy, Dunnigan type (FPLD), is a rare autosomal dominant genetic disorder characterized by gradual loss of sc fat from the extremities, commencing at the time of puberty. Excess fat deposition may occur in the face and neck area. Limited information is available about adipose tissue distribution in patients with FPLD. To investigate whether there is a unique pattern of...

Leptin is an adipocytokine that has an important role in energy homeostasis and therefore in the patho-physiology of obesity. Leptin levels are influenced by many factors such as gender, race, energy intake, fat mass, etc. The aim of our study is to investigate the relationship of circulating leptin levels to anthropometric parameters and to the subcutaneous and visceral fat tissue determined b...