Interactions of leukocytes with the vascular endothelium culminating in their diapedesis represent not only a crucial event in immune surveillance and defense but are also critically involved in the pathogenesis of many inflammatory diseases, including atherosclerosis. Our previous in vitro studies using atomic force microscopy measurement of monocyte-endothelial cell interaction have demonstra...

PURPOSE To quantify the fat in the levator muscle of patients with congenital ptosis, as related to clinical and epidemiological aspects of this disease. METHODS Twenty-two levator muscle samples of the superior eyelid from patients with congenital ptosis were morphometrically evaluated with aim of establishing a relationship between the fat quantity and age, sex, ptosis degree and levator mu...

BACKGROUND Many physiological and/or pathological conditions lead to muscle deconditioning, a well-described phenomenon characterized by a loss of strength and muscle power mainly due to the loss of muscle mass. Fatty infiltrations, or intermuscular adipose tissue (IMAT), are currently well-recognized components of muscle deconditioning. Despite the fact that IMAT is present in healthy human sk...

Grant Heatlie PhD MRCP,1 Bernd C. Cornelius MD,2 Andreas Kilkowski MD,2 Sanjay Prasad, MD MRCP,1 Mary N. Sheppard FRCPath,3 and Raad Mohiaddin FRCR FRCP FESC1 Royal Brompton Hospital, Cardiovascular Magnetic Resonance Unit, London, Great Britain, United Kingdom,1 Klinikum Ludwigshafen am Rhein gGmbH, ZIR und Medizinische B Klinik, Ludwigshafen, Germany,2 and Royal Brompton Hospital, Department ...

Background Chemical shift based water-fat separation methods can be used to reconstruct simultaneous fat and water images, thereby improving the sensitivity of fat detection using a positive fat contrast. The presence of fatty infiltration is a hallmark pathological feature of arrhythmogenic right ventricular cardiomyopathy (ARVC). Furthermore, the presence of fatty infiltration in chronic myoc...

This case report describes abnormalities in bilateral rectus capitis posterior minor muscles in one individual with persistent head and neck pain. These findings are muscle atrophy, fatty infiltration on magnetic resonance imaging, and electromyographic abnormalities compatible with denervated muscle. The objective of the study contained herein was to determine if fatty infiltration on magnetic...

A study was undertaken to determine the effects of long-term insulin therapy on the development and regression of lipid perturbations and experimental cholesterol atherosclerosis in rabbits: (1) Insulin administration for 15 days significantly reduced plasma lipid levels and free fatty acids in rabbits fed a high-cholesterol diet; it also inhibited the effects of a single dose of cholesterol. P...

1. Cystine fed to young albino rats as 10 per cent of the diet resulted in: (a) Portal hemorrhagic necrosis, resembling eclampsia, within 3 or 4 days. (b) A high mortality rate. (c) Fatty infiltration of hepatic cells in all rats surviving the initial acute lesion. (d) Cirrhosis of the liver in rats surviving more than 2 weeks. 2. 5 per cent dietary cystine produced marked fatty infiltration of...

OBJECTIVE To evaluate the fatty infiltration and atrophy of the supraespinatus in the pre- and postoperative of a rotator cuff lesion (RCL), by MRI. METHODS Ten patients with full-thickness rotator cuff tears who had undergone surgical arthroscopic rotator cuff repair between September and December 2011 were included. This is a prospective study, with analysis and comparison of fatty infiltra...

BACKGROUND Fatty infiltration of the liver usually has a diffuse pattern, but in very rare cases it presents as multiple focal lesions of the liver, mimicking metastases. A correct diagnosis is crucial to address prognosis and eventual treatment. CASE REPORT We present the case of a completely fit and asymptomatic patient referred for multiple bilateral liver metastases of unknown origin. She...