Febrile neutropenia is common in children with leukemia. Mucous membrane and skin are most common portals of entry for microorganisms in these patients. The aim of the present study was to find the prevalence of mucocutaneous findings infebrile neutropenic leukemic children. The authors prospectively examined children with fever with neutropenia in acute leukemia, aged 1-15 years, who were admi...

In a prospective randomized study, ceftazidime monotherapy was compared with a combination of ceftazidime plus cephalothin in 102 febrile neutropenic patients. Thirty bacteriologically documented infections, of which 23 were bacteremias, in 48 clinically assessable patients were treated with ceftazidime alone. Twenty-four bacteriologically proven infections, of which 18 were bacteremias, in 42 ...

INTRODUCTION Infection of neutropenic children treated with malignancies is even now the major cause of early morbidity and mortality. Febrile neutropenic attacks without complications are successfully treated with wide-spectrum anti-pseudomonal cephalosporins or carbapenems. OBJECTIVE To determine the efficacy and safety of imipenem in the treatment of febrile neutropenia in children with ca...

OBJECTIVE To determine the pattern of bacterial infections, isolate and identify the pathogenic bacteria and their sensitivity to different antibiotics during febrile episodes in paediatric patients with chemotherapy induced neutropenia from January to June 2000 at the Paediatric OncologyUunit of Combined Military Hospital, Rawalpindi (CMH RWP). PATIENTS AND METHODS The study material compris...

Infection-related mortality affects the overall survival rates of children who are receiving treatment for cancer. The leading cause of mortality is bacteremia and sepsis related to it in febrile neutropenic patients. All positive blood cultures of febrile neutropenic patients treated in the Department of Pediatric Hematology-Oncology, Cerrahpasa Medical School, between January 1995 and January...

BACKGROUND The aim of this study was to study trends in bacterial spectrum and susceptibility patterns of pathogens in adult febrile neutropenic patients during two time periods. METHODS We retrospectively reviewed the medical records of 379 adult oncology patients admitted with chemotherapy induced febrile neutropenia at our institute during years 2003 and 2006. RESULTS A total of 151 orga...

Respiratory viruses are a possible etiology of infections in pediatric febrile neutropenic patients, considering that they are the most frequent cause of fever in otherwise healthy children.1 We conducted a prospective, observational study, from March to December 2012, in Santa Casa de São Paulo, a busy quaternary public hospital in the largest and most populous city in Brazil, with the objecti...

BACKGROUND Febrile neutropenia (FN) is generally a complication of cancer chemotherapy in patients with hematological malignancies. OBJECTIVE To evaluate the febrile neutropenia episodes of hematological patients and their outcomes with respect to fungal pathogens, primary antifungal prophylaxis antifungal therapy. METHODS All consecutive patients older than 14 years of age and who develope...

backgrounds: neutropenia can be associated with life-threatening infections. gram negative and staphylococcal infections are the most common pathogens. the spectrum of bacterial isolates has changed considerably over the past four decades. the objective of the present study was to evaluate the pattern of bacterial and fungal infections in neutropenic pediatric patients.   methods: a non-randomi...

The use of colony-stimulating factors became an autonomous approach in complex supportive care blood tumors. By indications granulocyte factor (G-CSF) it is possible to reduce neutropenic period, perform optimal timing therapy, decrease a number infection complications. development and active new G-CSF drug formulation – pegfilgrastim do not the duration period significantly, but reduced freque...