Ferula persica, is the well-known species of the genus Ferula in Iran and has two varieties: persica and latisecta. They have both been extensively used in traditional medicine for a wide range of ailments. A great number of chemical compounds including sesquiterpene coumarins and polysulfides have been isolated from this plant. Fresh plant materials, crude extracts and isolated components of F...

Effect of hexane extract of Ferula jaeschkeana has been studied on the histological and biochemical constituents of the uterus of ovariectomized rats. Its administration caused remarkable increase in the height of luminal epithelium and the number of uterine glands. Its per se treatment also caused significant increase in the glycogen and protein contents and the activity of acid and alkaline p...

the fruit essential oil of ferula gummosa boiss., umbelliferae, which has been used as an antiepileptic remedy in iranian traditional medicine, was evaluated for anticonvulsant activity against experimental seizures. the essential oil had no effect against seizures induced by maximal electroshock. however, it protected mice against pentylenetetrazole-induced tonic seizures. the protective dose ...

Objective: Alpha-glucosidase, as a carbohydratase catalyses the liberation of alpha-glucose from the nonreducing end of some carbohydrates from foods in digestive tract.  Consequently, retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes is one of the therapeutic approaches to decrease the postprandial hyperglycemia. Recently, a great deal of attention has been pai...

The chemical composition of the essential oils of S. hierosolymitana Boiss. and S. multicaulis Vahl. var. simplicifolia Boiss. collected in Lebanon was studied by means of GC and GC-MS analysis. In all 115 compounds were identified: 82 for S hierosolymitana and 72 for S. multicaulis var. simplicifolia. The presence of carbonylic compounds (17%) characterizes the oil from S. hierosolymitana,whil...

Galbanic acid, a sesquiterpene coumarin from Ferula szowitsiana roots, was investigated for its potentiating effect on the antimicrobial activity of antibiotics as well as ethidium bromide, in 6 multidrug resistance (MDR) clinical isolates of Staphylococcus aureus. Galbanic acid had inhibitory effect on none of the isolated bacteria tested (up to 800 μg /ml). The MIC range of ciprofloxacin, tet...