Cell walls in the giant-celled green alga Valonia utricularis exhibit a “crossed-fibril” type of cell wall structure, wherein cellulose microfibrils (CMFs) are arranged uniform orientation each lamella. The CMF differs by 80° to 120° between neighboring lamellae. arrangement nascent CMFs deposited on regenerating protoplasts was investigated using an atomic force microscope for first time organ...

Our micromechanical experiments show that viscoelastic features of type-I collagen fibril at physiological temperatures display essential dependence on the frequency and speed of heating. For temperatures of 20–30 ◦C the internal friction has a sharp maximum for a frequency less than 2 kHz. Upon heating the internal friction displays a peak at a temperature Tsoft(v) that essentially depends on ...

We study the kinetics of prion fibril growth, described by the nucleated polymerization model analytically and by means of numerical experiments. The elementary processes of prion fibril formation lead us to a set of differential equations for the number of fibrils, their total mass, and the number of prion monomers. In difference to previous studies we analyze this set by explicitly taking int...

The inclusion of low-acetylated Gellan Gum and κ-carrageenan into amyloid fibril gels reinforces them mechanically, while preserving the surface functionality fibrils.

Fibrillogenesis of the amyloid beta-protein (Abeta) is believed to play a central role in the pathogenesis of Alzheimer's disease. Previous studies of the kinetics of Abeta fibrillogenesis showed that the rate of fibril elongation is proportional to the concentration of monomers. We report here the study of the temperature dependence of the Abeta fibril elongation rate constant, ke, in 0.1 M HC...

An apparatus that combines dynamic light scattering and Thioflavin T fluorescence detection is used to simultaneously probe fibril formation in polyglutamine peptides, the aggregating subunit associated with Huntington's disease, in vitro. Huntington's disease is a neurodegenerative disorder in a class of human pathologies that includes Alzheimer's and Parkinson's disease. These pathologies are...

The major hallmark of Alzheimer's disease is the deposition of plaques of amyloid fibrils formed from amyloid-β (Aβ) peptides. Kinetic studies have contributed significantly towards a mechanistic understanding of amyloid fibril self-assembly, however dynamic features of the aggregation process cannot be captured using ensemble methods. Here we present an assay for imaging Aβ42 aggregation dynam...

A distinctive feature of embryonic tendon development is the steady increase in collagen fibril diameter and associated improvement of tissue mechanical properties. A potential mechanical stimulus for these changes is slow stretching of the tendon during limb growth. Testing this hypothesis in vivo is complicated by the presence of other developmental processes including muscle development and ...

We introduce a green and efficient approach for removing per- polyfluoroalkyl substances (PFASs) based on the ?-lactoglobulin amyloid fibril membrane.